Results 41 to 50 of about 1,342,969 (307)

Heterogeneous responses of dorsal root ganglion neurons in neuropathies induced by peripheral nerve trauma and the antiretroviral drug stavudine [PDF]

, 2014
© 2014 The Authors. European Journal of Pain published by John Wiley & Sons Ltd on behalf of European Pain Federation - EFIC®. Funding sources E.K.B. was funded by a BBSRC PhD studentship. A.N., A.S.C.R. and T.P. were funded by a Wellcome Trust Strategic
Boateng, E K, Huang, W, Novejarque, A, Pheby, T, Rice, A S C   +4 more
core   +1 more source

Advancing Age Modulates Associations Between Cognitive Impairment and Brain Volumes in Early MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Cognitive impairment is common in multiple sclerosis (MS), but manifestations following the first demyelinating event are relatively unexplored. We investigated cross‐sectional associations between magnetic resonance imaging (MRI)–derived brain volumes and the presence of cognitive impairment outcomes five years after the first ...
Piriyankan Ananthavarathan, Marco Pitteri, Michael Foster, Sara Collorone, Sara Salama, Elisa Colato, Ferran Prados, Baris Kanber, Marios Yiannakas, Claudia A. M. Gandini Wheeler‐Kingshott, Indran Davagnanam, Frederik Barkhof, Declan Chard, Olga Ciccarelli, Ahmed Toosy   +14 more
wiley   +1 more source

miR-541 is associated with the prognosis of liver cirrhosis and directly targets JAG2 to inhibit the activation of hepatic stellate cells

BMC Gastroenterology
Background The activation of hepatic stellate cells (HSCs) has been emphasized as a leading event of the pathogenesis of liver cirrhosis, while the exact mechanism of its activation is largely unknown.
Jin-Pei Liu, Shao-Hua Song, Pei-Mei Shi, Xiao-Yu Qin, Bai-Nan Zheng, Shu-Qing Liu, Chen-Hong Ding, Xin Zhang, Wei-Fen Xie, Yi-Hai Shi, Wen-Ping Xu   +10 more
doaj   +1 more source

Impact of Bone-Modifying Agents on Post-Bone Metastasis Survival Across Cancer Types

Current Oncology
Background: Bone metastasis is associated with a poor prognosis. Bone-modifying agents (BMA) are commonly used for the prevention or treatment of skeletal-related events (SRE) in patients with bone metastasis; however, whether or not treatment with BMA ...
Hironari Tamiya, Kazumi Nishino, Yuji Kato, Reina Nakahashi-Kato, Yurika Kosuga-Tsujimoto, Shota Kinoshita, Rie Suzuki, Makiyo Watanabe, Toru Wakamatsu, Shigeki Kakunaga, Satoshi Takenaka   +10 more
doaj   +1 more source

A Message Passing Approach to Biomedical Relation Classification for Drug–Drug Interactions

Applied Sciences, 2022
The task of extracting drug entities and possible interactions between drug pairings is known as Drug–Drug Interaction (DDI) extraction. Computer-assisted DDI extraction with Machine Learning techniques can help streamline this expensive and time ...
Dimitrios Zaikis, Christina Karalka, Ioannis Vlahavas   +2 more
doaj   +1 more source

The contribution of teamwork, thinking styles, and innovation towards knowledge management [PDF]

, 2009
Knowledge management can be enhanced by creating conditions that facilitate knowledge creation, thus the concepts of teamwork,thinking styles, and innovation are central to the effective utilisationof knowledge.
Ratnasingam, Malini
core  

Spatial and Volumetric Characteristics of Glioblastoma: Associations With Clinical Presentation and Survival

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We aim to comprehensively analyze how regional tumor and edema characteristics are associated with clinical presentations and survival outcomes in a large cohort of glioblastoma patients. Methods Patients with IDH‐wildtype glioblastoma who received brain MRI from 2010 to 2023 were included.
Daniel J. Zhou, Marc Jaskir, Julian Gal, Yombe Fonkeu, Christos Davatzikos, MacLean P. Nasrallah, Jose Garcia, Stephen J. Bagley, Arati Desai, Richard E. Phillips, Steven Tobochnik, Colin A. Ellis, James J. Gugger, Nishant Sinha, Joel M. Stein, Kathryn A. Davis   +15 more
wiley   +1 more source

European guidelines from the EHTG and ESCP for Lynch syndrome: an updated third edition of the Mallorca guidelines based on gene and gender

BJS (British Journal of Surgery), EarlyView., 2020
Recommendations for clinical and molecular identification of LS, surgical and endoscopic management of LS‐associated colorectal cancer and preventive measures for cancer were produced. The emphasis was on surgical and gastroenterological aspects of the cancer spectrum.
T. T. Seppälä, A. Latchford, I. Negoi, A. Sampaio Soares, R. Jimenez‐Rodriguez, L. Sánchez‐Guillén, D. G. Evans, N. Ryan, E. J. Crosbie, M. Dominguez‐Valentin, J. Burn, M. Kloor, M. von Knebel Doeberitz, F. J. B. van Duijnhoven, P. Quirke, J. R. Sampson, P. Møller, G. Möslein, on behalf of the European Hereditary Tumour Group (EHTG) and European Society of Coloproctology (ESCP)   +18 more
wiley   +1 more source

Calcium-Enriched Magnetic Core–Shell Mesoporous Nanoparticles for Potential Application in Bone Regeneration

Nanomaterials
Magnetite (Fe3O4) nanoparticles are biocompatible, non-toxic, and easily functionalized. Coating them with mesoporous silica (mSiO2) offers high surface area, pore volume, and tunable surface chemistry for drug loading.
Despoina Kordonidou, Georgia K. Pouroutzidou, Nikoletta Florini, Ioannis Tsamesidis, Konstantina Kazeli, Dimitrios Gkiliopoulos, George Vourlias, Makis Angelakeris, Philomela Komninou, Panos Patsalas, Eleana Kontonasaki   +10 more
doaj   +1 more source

Usability Evaluation in Virtual Environments: Classification and Comparison of Methods [PDF]

, 2001
Virtual environments (VEs) are a relatively new type of human-computer interface in which users perceive and act in a three-dimensional world. The designers of such systems cannot rely solely on design guidelines for traditional two-dimensional ...
Bowman, Doug A., Gabbard, J., Hix, D.
core   +1 more source