Results 201 to 210 of about 1,421,138 (293)

Evaluating the optimal duration of medication treatment for opioid use disorder

open access: yesAddiction, EarlyView.
Abstract Background and aims Clinicians have little guidance on the ideal length of time patients should remain on medication treatment for opioid use disorder (MOUD) before being able to safely discontinue MOUD. This study estimated how the risk of all‐cause mortality changes with the duration of MOUD, controlling for patient characteristics that ...
Corey J. Hayes   +5 more
wiley   +1 more source

Type I and II Interferons Drive Abacavir Hypersensitivity via Treg Suppression and T‐Cell Enhancement in Immunocompetent HLA‐Transgenic Mice

open access: yesAllergy, EarlyView.
Upregulated HLA‐B*57:01 expression in Tg/KO mice amplifies abacavir‐specific CD8+ T‐cell activation, driven by enhanced antigen presentation. Abacavir treatment induces robust pDC expansion and IFN‐α production, which selectively suppresses memory Treg populations.
SuJin Hwang   +8 more
wiley   +1 more source

Fairness, Consistency and Bias in the RACS General Surgery Fellowship Examination

open access: yesANZ Journal of Surgery, EarlyView.
ABSTRACT Introduction The General Surgery Fellowship Examination is the final hurdle examination before being eligible for fellowship of the Royal Australasian College of Surgeons. The purpose of this study was to assess the consistency and reliability of this examination, specifically whether there was evidence of systemic gender bias. Methods This is
Douglas Stupart   +6 more
wiley   +1 more source

The Provenance of Silver in the Viking‐Age Hoard From Bedale, North Yorkshire

open access: yesArchaeometry, EarlyView.
ABSTRACT The acquisition of silver was a key motive propelling the Viking expansion out of Scandinavia; identifying the sources of Viking silver during the early part of the Viking Age can provide critical insights into the relative significance of western European and eastern, Islamic wealth in the Viking expansion.
Jane Kershaw   +5 more
wiley   +1 more source

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