Results 31 to 40 of about 1,422,891 (308)

A novel HSP90 inhibitor targeting the C-terminal domain attenuates trastuzumab resistance in HER2-positive breast cancer

open access: yesMolecular Cancer, 2020
Trastuzumab resistance in HER2-positive breast cancer is associated with a poorer prognosis. HSP90 is thought to play a major role in such resistance, but N-terminal inhibitors of this target have had little success.
Jung Min Park   +11 more
doaj   +1 more source

Using ANP and QFD methodologies to analyze eco-efficiency requirements in an electronic supply chain

open access: yesCleaner Engineering and Technology, 2021
The concept of eco-efficiency is an important step in the move towards sustainable development. In the present day business, organizations have to take care of both the economic growth and environmental impact.
Rakesh R. Menon, V. Ravi
doaj   +1 more source

Analysis of enablers of sustainable supply chain management in electronics industries: The Indian context

open access: yesCleaner Engineering and Technology, 2021
Globalization has led organizations to think beyond economic benefit goals and move towards sustainable supply chains to address their business's societal and environmental concerns.
Rakesh R. Menon, V. Ravi
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Exploring critical success factors influencing adoption of digital twin and physical internet in electronics industry using grey-DEMATEL approach

open access: yesDigital Business, 2021
Digital twin and physical internet adoption based on advanced digital technologies is gaining significance in the recent times. Digital twin is one of the enabling technologies that link actual physical system with its virtual depiction using advanced ...
T.S. Deepu, V. Ravi
doaj   +1 more source

State of New York Public Employment Relations Board Decisions from May 27, 2011 [PDF]

open access: yes, 2011
BD_Mtng_5_27_2011.pdf: 547 downloads, before Oct.
New York State Public Employment Relations Board
core   +1 more source

Treatment with a New Peroxisome Proliferator-Activated Receptor Gamma Agonist, Pyridinecarboxylic Acid Derivative, Increases Angiogenesis and Reduces Inflammatory Mediators in the Heart of Trypanosoma cruzi-Infected Mice [PDF]

open access: yes, 2017
Trypanosoma cruzi infection induces an intense inflammatory response in diverse host tissues. The immune response and the microvascular abnormalities associated with infection are crucial aspects in the generation of heart damage in Chagas disease.
Carta, Davide   +9 more
core   +2 more sources

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu   +10 more
wiley   +1 more source

Borophene‐Based Ultrasensitive and Broadband Photodetectors

open access: yesAdvanced Materials Interfaces
Photodetectors based on vertical junctions between 2D materials and silicon offer enhanced sensitivity, reduced size, and better integrability with other systems. In these detectors, 2D materials are typically grown on metallic crystalline substrates and
Yaser Abdi   +7 more
doaj   +1 more source

Metabolic perturbations in methicillin-resistant Staphylococcus aureus induced by Psidium guajava ethanolic leaf extract

open access: yesLife Sciences, Medicine and Biomedicine, 2023
Psidium guajava ethanolic leaf extract (PGele) showed good antibacterial activity against Staphylococcus aureus in various in vitro and in vivo studies.
Ailyn Manglicmot Yabes   +1 more
doaj   +1 more source

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