Results 41 to 50 of about 2,259,746 (339)

Protective Effect of Biflavones from Platonia insignis Mart. against Ethidium Bromide-Induced Lethality in Staphylococcus aureus

Compounds, 2023
Brazilian flora are highly diverse and have great potential for research into new medicines of plant origin. Platonia insignis Mart. is a fruit tree from the Amazon region with several potential pharmacological applications already demonstrated.
Andressa Sabrina Guimarães Moura, Júlia de Andrade Ferreira Barreto, Andressa Kelly Ferreira e Silva, Maria Luísa Lima Barreto do Nascimento, Emanuelly Elanny Andrade Pinheiro, Arkellau Kenned Silva Moura, João Marcelo de Castro e Sousa, José de Souza Lima-Neto, Antonia Maria das Graças Lopes Citó, Henrique Douglas Melo Coutinho, Humberto Medeiros Barreto   +10 more
doaj   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Target choice and exon skipping regulate CRISPR-directed gene editing of NRF2 in head/neck and esophageal cancer cells

Molecular Therapy: Oncology
Head and neck cancer (HNC) is the seventh most diagnosed cancer, with a predicted 30% increase annually by 2030. Conventional treatment is often combinatorial involving chemotherapy and radiation therapy, immunotherapy, and surgery, but over time ...
Natalia Rivera-Torres, Lauren E. Skelly, John A. Rogowskyj, Guadalupe Aguilar, Kelly Banas, Pawel Bialk, Eric B. Kmiec   +6 more
doaj   +1 more source

HIV modelling in a labour force [PDF]

, 2006
A section of the workforce employed by a certain company has been found to be HIV positive. Demographic, social and clinical data has been gathered by medical practitioners at the company's Wellness Centre for each patient from the time they were put in ...
Masinga, L.C., Myburgh, C., Sherwell, D.S.   +2 more
core  

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Stimulated emission and excited-state absorption at room temperature on the 550 nm-laser transition in Er3+ doped YAlO3 [PDF]

, 1994
A pump- and probe-beam technique is used for measuring time-resolved and cw-pumped excited-state absorption (ESA) and stimulated-emission (SE) spectra of Er3+:YAlO3 with high resolution.
Heumann, E., Huber, G., Pollnau, M.
core   +3 more sources

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Motor Function and Manual Ability in Children with Cerebral Palsy: A Primary Report

International Journal of Child Development and Mental Health, 2017
This descriptive study aims to describe the motor type, topographical distribution and motor function of lower limbs, and the manual ability of upper limbs.
Aye Myint Thu, Thant Thant Aung, Khin Mar Myint, Aye Aye Myint   +3 more
doaj  

Detection of Non-Technical Losses on a Smart Distribution Grid Based on Artificial Intelligence Models

Energies
Non-technical losses (NTL) have been a growing problem over the years, causing significant financial losses for electric utilities. Among the methods for detecting this type of loss, those based on Artificial Intelligence (AI) have been the most popular.
Murilo A. Souza, Hugo T. V. Gouveia, Aida A. Ferreira, Regina Maria de Lima Neta, Otoni Nóbrega Neto, Milde Maria da Silva Lira, Geraldo L. Torres, Ronaldo R. B. de Aquino   +7 more
doaj   +1 more source

Primary Meningococcal Polyarthritis in an Adult Woman

Case Reports in Medicine, 2015
Primary joint infection caused by the Gram-negative bacteria Neisseria meningitidis is rare. Normally, joint involvement comes secondary to meningitis or severe sepsis caused by this agent. When primary arthritis is seen, monoarthritis is the most common
José Celso Giordan Cavalcanti Sarinho, Marília Soares e Silva Arcadipane, Graziela Tavares Miola Menezes, Danilo Fernando Costa Duarte, Waldenise Cossermelli, Ivan Aprahamian   +5 more
doaj   +1 more source