Results 21 to 30 of about 140,185 (295)

Safety and tolerability of an anti-CD19 monoclonal antibody, MEDI-551, in subjects with systemic sclerosis: a phase I, randomized, placebo-controlled, escalating single-dose study

Arthritis Research & Therapy, 2016
BackgroundSystemic sclerosis (SSc) is a clinically heterogeneous, life-threatening disease characterized by fibrosis, microvasculopathy, and autoimmunity. Extensive nonclinical and clinical data implicate B cells in the pathogenesis of SSc.
E. Schiopu, S. Chatterjee, V. Hsu, A. Flor, Daniel M. Cimbora, K. Patra, W. Yao, Jing Li, K. Streicher, K. McKeever, B. White, E. Katz, J. Drappa, Sarah Sweeny, R. Herbst   +14 more
semanticscholar   +1 more source

Study on Dissolution of Al₂Cu in Al-4.3Cu and A205 Cast Alloys

Metals, 2020
Evolution of microstructure in a binary Al-Cu system (Al-4.3Cu) and a commercially alloyed Al-Cu system (A205) during solution heat treatment was investigated using optical microscopy (OM), scanning electron microscopy (SEM), wavelength-dispersive X-ray ...
Mohammadreza Zamani, Ilia Belov, Emma Sjölander, Anton Bjurenstedt, Ehsan Ghassemali, Salem Seifeddine   +5 more
doaj   +1 more source

Twin-Delayed Deep Deterministic Policy Gradient for Low-Frequency Oscillation Damping Control

Energies, 2021
Due to the large scale of power systems, latency uncertainty in communications can cause severe problems in wide-area measurement systems. To resolve this issue, a significant amount of past work focuses on using emerging technology, including machine ...
Qiushi Cui, Gyoungjae Kim, Yang Weng
doaj   +1 more source

Diagnostic and Therapeutic Challenges in a Patient with Radiation Retinopathy Complicated by Corticosteroid-Induced Central Serous Chorioretinopathy

Medicina, 2022
Central serous chorioretinopathy (CSC) is a common chorioretinal disorder. It has been postulated that impaired retinal pigment epithelium and hyperpermeability of the choriocapillaris may be involved in the development of CSC, but the exact ...
Michał Chrząszcz, Natalia Mackiewicz, Weronika Pociej-Marciak, Bożena Romanowska-Dixon, Agnieszka Kubicka-Trząska, Maciej Gawęcki, Izabella Karska-Basta   +6 more
doaj   +1 more source

The Effects of Fe-Particles on the Tensile Properties of Al-Si-Cu Alloys

Metals, 2016
The effect of Fe-rich particles has been a topic for discussion in the aluminum casting industry because of the negative impact they exert on the mechanical properties.
Anton Bjurenstedt, Salem Seifeddine, Anders E. W. Jarfors   +2 more
doaj   +1 more source

A Novel Peroxisome Proliferator-activated Receptor (PPAR)α Agonist and PPARγ Antagonist, Z-551, Ameliorates High-fat Diet-induced Obesity and Metabolic Disorders in Mice*

Journal of Biological Chemistry, 2015
Background: Obesity is one of the principal causes of metabolic syndrome. Results: A novel PPARα agonist/γ antagonist, Z-551, ameliorates obesity, insulin resistance, and impairment of glucose and lipid metabolisms in mice.
Yoshihiro Shiomi, T. Yamauchi, Masato Iwabu, Miki Okada-Iwabu, R. Nakayama, Y. Orikawa, Y. Yoshioka, Koichiro Tanaka, K. Ueki, T. Kadowaki   +9 more
semanticscholar   +1 more source

Records of the Marbled Cat Pardofelis marmorata and the Asiatic Golden Cat Catopuma temminckii (Mammalia: Carnivora: Felidae) from the community forests surrounding the Dzükou Valley in Nagaland, India

Journal of Threatened Taxa, 2019
Northeastern India, situated within the Indo-Burma and eastern Himalaya biodiversity hotspot complex, is known for its high diversity of wild felid species.
Bhavendu Joshi, Biang La Nam Syiem, Rokohebi Kuotsu, Arjun Menon, Jayanta Gogoi, Varun Rshav Goswami, Divya Vasudev   +6 more
doaj   +1 more source

Distance Matrix of a Class of Completely Positive Graphs: Determinant and Inverse

Special Matrices, 2020
A real symmetric matrix A is said to be completely positive if it can be written as BBt for some (not necessarily square) nonnegative matrix B. A simple graph G is called a completely positive graph if every matrix realization of G that is both ...
Das Joyentanuj, Jayaraman Sachindranath, Mohanty Sumit   +2 more
doaj   +1 more source

Domain-Swapped Dimer of Pseudomonas aeruginosa Cytochrome c 551: Structural Insights into Domain Swapping of Cytochrome c Family Proteins

PLoS ONE, 2015
Cytochrome c (cyt c) family proteins, such as horse cyt c, Pseudomonas aeruginosa cytochrome c 551 (PA cyt c 551), and Hydrogenobacter thermophilus cytochrome c 552 (HT cyt c 552), have been used as model proteins to study the relationship between the ...
S. Nagao, Mariko Ueda, H. Osuka, H. Komori, H. Kamikubo, M. Kataoka, Y. Higuchi, S. Hirota   +7 more
semanticscholar   +1 more source

Initial Impact of Different Feeding Methods on Feed Intake Time in Stabled Icelandic Horses

Animals
The natural behaviour of horses is to spend the majority of their time on feed intake The feeding of stabled horses is, however, often far from that, as their feed intake is limited to their nutritional requirements.
Sveinn Ragnarsson, Sigríður Vaka Víkingsdóttir, Guðrún Jóhanna Stefánsdóttir   +2 more
doaj   +1 more source