Results 51 to 60 of about 140,185 (295)
Advanced Science, EarlyView.Dietary habits play a key role in chronic diseases, and higher annual consumption of fruit and vegetable may lower risk of dementia. Artificial intelligence predicts the lipid‐like compound α‐Amyrin (αA) from plants with edible peels as a drug candidate against Alzheimer's disease.
Shu‐Qin Cao +36 more
wiley +1 more source
Psychiatry InternationalThis study used bibliometric analysis to investigate the research on Attention-Deficit/Hyperactivity Disorder (ADHD) in pediatric populations between January 2014 and January 2024.
Mohamed E. Elnageeb +9 more
doaj +1 more source
Annals of Oncology, 2019 Background Anti-PD1/PD-L1 directed immune checkpoint inhibitors (ICI) are widely used to treat patients with advanced non-small-cell lung cancer (NSCLC). The activity of ICI across NSCLC harboring oncogenic alterations is poorly characterized. The aim of
J. Mazières +37 more
semanticscholar +1 more source
Endocytic Control of Cell‐Autonomous and Non‐Cell‐Autonomous Functions of p53
Advanced Science, EarlyView.NUMB Ex3‐containing isoforms localize to the plasma membrane, where they recruit p53 through SNX9 and direct it to multivesicular bodies and exosomes. Exported p53 is taken up by neighboring cells and activates nuclear programs, revealing an intercellular, exosome‐based pathway that might help establish a tumor‐suppressive microenvironment.
Roberta Cacciatore +20 more
wiley +1 more source
cDC1 Subtype‐Specific In Vivo Targeting of Liposomes
Advanced Science, EarlyView.Dendritic cells, particularly the cDC1 subtype, offer a promising target for drug delivery via liposomes due to their pivotal role in immune regulation, allowing for amplified therapeutic responses. Herein, we show an integration of physicochemical characterization and cell experiments to achieve effective in vivo cDC1 targeting through anti‐CLEC9A ...
Maximilian Schaaf +11 more
wiley +1 more source
β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma
Advanced Science, EarlyView.β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto +20 more
wiley +1 more source
The bibliometric analysis of scholarly production: How great is the impact?
Scientometrics, 2015 Bibliometric methods or “analysis” are now firmly established as scientific specialties and are an integral part of research evaluation methodology especially within the scientific and applied fields.
O. Ellegaard, J. Wallin
semanticscholar +1 more source
T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities
Advanced Science, EarlyView.T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu +7 more
wiley +1 more source
Robust Fractional Low Order Adaptive Linear Chirplet Transform and Its Application to Fault Analysis
EntropyTime-frequency analysis (TFA) technology is an important tool for analyzing non-Gaussian mechanical fault vibration signals. In the complex background of infinite variance process noise and Gaussian colored noise, it is difficult for traditional methods ...
Junbo Long +3 more
doaj +1 more source
A Conceptual Framework for Integration of Evidence-Based Design with Lighting Simulation Tools
Buildings, 2017 The use of lighting simulation tools has been growing over the past years which has improved lighting analysis. While computer simulations have proven to be a viable tool for analyzing lighting in physical environments, they have difficulty in assessing ...
Anahita Davoodi +3 more
doaj +1 more source