Results 171 to 180 of about 10,718 (215)
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Registration of Soybean Germplasm Line LN89‐5699, Resistant to Soybean Cyst Nematode
Crop Science, 1994C D Nickell, G R Noel, R L Bernard
exaly +2 more sources
Rechtspraak 5699. Van Rijn / Voolstra (TvAR 2012/5699)
Tijdschrift voor Agrarisch Recht, 2012exaly +2 more sources
Cancer Research, 2022
Abstract Background: Aberrant expression of epigenetic regulators is often associated with pathogenesis. Histone H3K4 methyltransferase, known as KMT2A, has been implicated in regulation of chromosome segregation, mitosis and DNA replication in pediatric leukemia and myeloma. However, the role of KMT2A expression in solid tumors is under-
Liang Sha +17 more
openaire +1 more source
Abstract Background: Aberrant expression of epigenetic regulators is often associated with pathogenesis. Histone H3K4 methyltransferase, known as KMT2A, has been implicated in regulation of chromosome segregation, mitosis and DNA replication in pediatric leukemia and myeloma. However, the role of KMT2A expression in solid tumors is under-
Liang Sha +17 more
openaire +1 more source
Cancer Research, 2023
Abstract Introduction: Poly (ADP-ribose) polymerase (PARP) and ataxia telangiectasia and Rad3-related (ATR) inhibitors target key DNA damage response (DDR) kinases. PARP inhibitors (PARPi) suppress the catalytic activity of PARP and trap PARP in a complex with damaged DNA, resulting in the accumulation of unrepaired single-strand breaks (
Claire C. Villette +9 more
openaire +1 more source
Abstract Introduction: Poly (ADP-ribose) polymerase (PARP) and ataxia telangiectasia and Rad3-related (ATR) inhibitors target key DNA damage response (DDR) kinases. PARP inhibitors (PARPi) suppress the catalytic activity of PARP and trap PARP in a complex with damaged DNA, resulting in the accumulation of unrepaired single-strand breaks (
Claire C. Villette +9 more
openaire +1 more source
Cancer Research, 2017
Abstract The purpose of this study was to explore the potential of urine DNA biomarkers for the early detection of primary hepatocellular carcinoma (HCC). HCC is an aggressive disease with a 5-year survival rate of 26% in early-stage cancers, and a mere 2% in later stages. The most commonly used screening biomarker for HCC is serum alpha-
Surbhi Jain +7 more
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Abstract The purpose of this study was to explore the potential of urine DNA biomarkers for the early detection of primary hepatocellular carcinoma (HCC). HCC is an aggressive disease with a 5-year survival rate of 26% in early-stage cancers, and a mere 2% in later stages. The most commonly used screening biomarker for HCC is serum alpha-
Surbhi Jain +7 more
openaire +1 more source
Cancer Research, 2020
Abstract Background Myeloid-derived suppressor cells (MDSC) elicit a range of suppressive functions that inhibit normal T cell responses and promote non-responsiveness to immune checkpoint blockade. While CD33 does not appear to play a significant role in differentiated myeloid cells, in immature myeloid cells CD33 signaling via ligand ...
Victoria Smith +6 more
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Abstract Background Myeloid-derived suppressor cells (MDSC) elicit a range of suppressive functions that inhibit normal T cell responses and promote non-responsiveness to immune checkpoint blockade. While CD33 does not appear to play a significant role in differentiated myeloid cells, in immature myeloid cells CD33 signaling via ligand ...
Victoria Smith +6 more
openaire +1 more source
Cancer Research, 2012
Abstract Circulating bone marrow-derived Mesenchymal Stem Cells (MSCs) can differentiate into cells of the mesoderm lineage and have an innate tropism for tumor tissue in response to the inflammatory microenvironment present in malignant lesions. MSCs have been detected in the perivascular space of many tumors, including prostate.
Shuangling Chen +5 more
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Abstract Circulating bone marrow-derived Mesenchymal Stem Cells (MSCs) can differentiate into cells of the mesoderm lineage and have an innate tropism for tumor tissue in response to the inflammatory microenvironment present in malignant lesions. MSCs have been detected in the perivascular space of many tumors, including prostate.
Shuangling Chen +5 more
openaire +1 more source
Cancer Research, 2010
Abstract Obesity has been associated with increased colon cancer risk. Although the molecular pathways underlying the obesity-colon cancer link are unknown, one hypothesis is obesity induces a chronic inflammatory state which increases cancer risk. MicroRNAs (miRs) are small noncoding RNAs that regulate gene expression.
Susan E. Olivo-Marston +6 more
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Abstract Obesity has been associated with increased colon cancer risk. Although the molecular pathways underlying the obesity-colon cancer link are unknown, one hypothesis is obesity induces a chronic inflammatory state which increases cancer risk. MicroRNAs (miRs) are small noncoding RNAs that regulate gene expression.
Susan E. Olivo-Marston +6 more
openaire +1 more source