Results 321 to 330 of about 1,476,815 (405)

Evenly Distributed Microporous Structure and E7 Peptide Functionalization Synergistically Accelerate Osteogenesis and Angiogenesis in Engineered Periosteum

open access: yesAdvanced Science, Volume 12, Issue 11, March 20, 2025.
The periosteum plays a crucial role in the repair of large bone defects. The artificial periosteum is successfully engineered with a porous structure and enhanced functionality by integrating P407 (Poloxam 407) and E7 peptides. These modifications are discovered to enhance proliferation, recruitment, and osteogenic differentiation of MSCs and to ...
Qihong Li   +10 more
wiley   +1 more source

Homozygous AA Genotype of IL-17A and 14-bp Insertion Polymorphism in HLA-G 3'UTR Are Associated with Increased Risk of Gestational Diabetes Mellitus. [PDF]

open access: yesInt J Environ Res Public Health
de Souza ATB   +8 more
europepmc   +1 more source

NaBC1 Boron Transporter Enables Myoblast Response to Substrate Rigidity via Fibronectin‐Binding Integrins

open access: yesAdvanced Science, EarlyView.
Cells transduce the rigidity of the environment into biochemical cues through mechanotransductive cascades that modulate cell behavior. Here, a novel role for the boron transporter NaBC1 is identified as a mechanotransducer involved in regulating cell behavior via specific crosstalk with fibronectin‐binding integrins.
Juan Gonzalez‐Valdivieso   +9 more
wiley   +1 more source

PCSK9 Promotes the Malignancy of Triple‐negative Breast Cancer Cells by Reducing Cholesterol Levels at the Plasma Membrane to Activate EGFR and HER3

open access: yesAdvanced Science, EarlyView.
By decreasing cholesterol and lipid raft levels in the plasma membrane, proprotein convertase subtilisin/kexin type 9 (PCSK9) boosts human epidermal growth factor receptor 1 and 3 (EGFR and HER3) activation, driving tumor growth and metastasis in triple‐negative breast cancer (TNBC).
Tianhong Li, Renfei Wu, Kathy Qian Luo
wiley   +1 more source

Icarisid Ⅱ modulates mitochondrial dynamics for anti-HBV activity. [PDF]

open access: yesFront Pharmacol
Liu Z   +7 more
europepmc   +1 more source

Programmed Fabrication of Vesicle‐Based Prototissue Fibers with Modular Functionalities

open access: yesAdvanced Science, Volume 12, Issue 16, April 24, 2025.
The fabrication of freestanding vesicle‐based prototissue fibers is reported. The lengths, diameters, and shapes of the fibers can be well‐controlled. Multimodular fibers with different prototissues can be fabricated. Focusing on modularity, manipulation functionalities are obtained when connected with magnetic fibers.
Tomoya Kojima   +3 more
wiley   +1 more source

ROS‐Responsive Microneedle Patches Enable Peri‐Lacrimal Gland Therapeutic Administration for Long‐Acting Therapy of Sjögren's Syndrome‐Related Dry Eye

open access: yesAdvanced Science, Volume 12, Issue 16, April 24, 2025.
A new strategy for constructing smart gel‐based MN patches is developed to overcome the insufficient drug delivery of eye drops to the lacrimal gland. The gel‐based MN patches achieved long‐acting drug release in a ROS‐responsive manner, and separable base in a temperature‐responsive manner.
Jingqing Mu   +10 more
wiley   +1 more source

Rescue stenting after failed mechanical thrombectomy: The RES-CAT study. [PDF]

open access: yesEur Stroke J
Collet-Vidiella R   +35 more
europepmc   +1 more source

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