Results 191 to 200 of about 142,830 (293)

Efficacy and Safety of Escitalopram for Major Depressive Disorder in Children and Adolescents: A Systematic Review and Meta-Analysis with Age-Specific Findings. [PDF]

open access: yesNeuropsychiatr Dis Treat
Maneeton B   +8 more
europepmc   +1 more source

Improving protein secretion with autophagy‐inhibiting or proteasome‐activating small molecules

open access: yesJournal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND Therapeutic proteins are produced frequently by mammalian cells in large‐scale bioreactors. As a result, producer cells are exposed to a chemically (nutrients, gas exchange, target protein overexpression) and physically (shear due to mixing) stressful environment, which can lead to endoplasmic reticulum (ER) stress and loss of ...
R Chauncey Splichal   +2 more
wiley   +1 more source

Positive developmental cascades: Strength development reduces support needs in children

open access: yesJCPP Advances, EarlyView.
Abstract Background Strength development in children across a range of psychiatric diagnoses may reduce needs for mental health, social, and functioning support over time. A strength‐based adjunct to child and adolescent mental health may foster the developmental context most helpful for achieving desired outcomes with positive developmental cascading ...
Melody R. Altschuler   +12 more
wiley   +1 more source

A framework for integrating health‐related social needs education into electronic health record clinical pathways

open access: yesJournal of Hospital Medicine, EarlyView.
Abstract Health‐related social needs (HRSN) significantly influence patient outcomes, yet they are rarely integrated into point‐of‐care decision‐making. We developed a process to embed HRSN‐informed and HRSN‐targeted care recommendations directly into three electronic health record‐integrated high‐use clinical pathways—cirrhosis, diabetes, and ...
Karthik Warke Rohatgi   +5 more
wiley   +1 more source

Climatic Drivers of the Area Burned by Winter Wildfires in Northern Italy

open access: yesInternational Journal of Climatology, EarlyView.
This study investigates winter wildfires occurring between November and April in northern Italy over the period 2008–2022. By integrating high‐resolution burned‐area data with gridded climatic indices derived from 150 weather stations, it identifies spatial and temporal wildfire patterns, highlights the most fire‐prone mountain areas through pixel ...
Alice Baronetti   +2 more
wiley   +1 more source

Barriers and facilitators to the national scale‐up of a preterm standardised parenteral nutrition system: A mixed‐methods evaluation

open access: yesJPGN Reports, EarlyView.
Abstract Objective Standardising parenteral nutrition (PN) care for preterm infants is recommended to enhance safety, outcomes and efficiency, however implementation at scale remains challenging. In 2021, Ireland scaled‐up a standardised parenteral nutrition (SPN) system comprising SPN formulations and dosing protocol.
Sarah Fenton   +7 more
wiley   +1 more source

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