Efficacy and Safety of Escitalopram for Major Depressive Disorder in Children and Adolescents: A Systematic Review and Meta-Analysis with Age-Specific Findings. [PDF]
Maneeton B +8 more
europepmc +1 more source
Improving protein secretion with autophagy‐inhibiting or proteasome‐activating small molecules
Abstract BACKGROUND Therapeutic proteins are produced frequently by mammalian cells in large‐scale bioreactors. As a result, producer cells are exposed to a chemically (nutrients, gas exchange, target protein overexpression) and physically (shear due to mixing) stressful environment, which can lead to endoplasmic reticulum (ER) stress and loss of ...
R Chauncey Splichal +2 more
wiley +1 more source
Precise genome modification of agrobacterium based on one-step homologous recombination via endogenous transfer DNA. [PDF]
Liu Y +7 more
europepmc +1 more source
Positive developmental cascades: Strength development reduces support needs in children
Abstract Background Strength development in children across a range of psychiatric diagnoses may reduce needs for mental health, social, and functioning support over time. A strength‐based adjunct to child and adolescent mental health may foster the developmental context most helpful for achieving desired outcomes with positive developmental cascading ...
Melody R. Altschuler +12 more
wiley +1 more source
Correction: <i>Measuring older people's socioeconomic position: a scoping review of studies of self-rated health, health service and social care use</i>. [PDF]
europepmc +1 more source
The value of intratumoral and peritumoral ultrasound radiomics in predicting lateral cervical lymph node metastasis in papillary thyroid carcinoma: a multicenter study of five hospitals. [PDF]
Jin K +6 more
europepmc +1 more source
Abstract Health‐related social needs (HRSN) significantly influence patient outcomes, yet they are rarely integrated into point‐of‐care decision‐making. We developed a process to embed HRSN‐informed and HRSN‐targeted care recommendations directly into three electronic health record‐integrated high‐use clinical pathways—cirrhosis, diabetes, and ...
Karthik Warke Rohatgi +5 more
wiley +1 more source
Climatic Drivers of the Area Burned by Winter Wildfires in Northern Italy
This study investigates winter wildfires occurring between November and April in northern Italy over the period 2008–2022. By integrating high‐resolution burned‐area data with gridded climatic indices derived from 150 weather stations, it identifies spatial and temporal wildfire patterns, highlights the most fire‐prone mountain areas through pixel ...
Alice Baronetti +2 more
wiley +1 more source
Abstract Objective Standardising parenteral nutrition (PN) care for preterm infants is recommended to enhance safety, outcomes and efficiency, however implementation at scale remains challenging. In 2021, Ireland scaled‐up a standardised parenteral nutrition (SPN) system comprising SPN formulations and dosing protocol.
Sarah Fenton +7 more
wiley +1 more source
Radiographic comparison of lumbar vertebral morphology between cats with six and seven lumbar vertebrae. [PDF]
Kim G +5 more
europepmc +1 more source

