Results 171 to 180 of about 1,386,180 (335)

Additive‐Free Ti3C2Tx MXene Actuator with Large Deformation, Programmability, and High‐Humidity Stability via Precise Interlayer Spacing Control Engineering

open access: yesAdvanced Science, EarlyView.
By sequentially assembling MXene nanosheets with significant size differences, a multistimulus responsive additive‐free MXene actuator with gradient structure is obtained. An innovative cyclic low‐temperature annealing‐rehydration technology is proposed, which achieves precise control of interlayer d‐spacing, initial shape, and actuation behavior of ...
Haowen Zheng   +13 more
wiley   +1 more source

PARPi Combining Nanoparticle LIN28B siRNA for the Management of Malignant Ascites

open access: yesAdvanced Science, EarlyView.
This study demonstrates that co‐inhibition of LIN28B and PARP using siLin28b/DSSP@lip‐PEG‐FA nanoparticles in combination with the PARP inhibitor BMN673 effectively suppresses the accumulation of malignant ascites associated with advanced cancers.
Yan Fang   +13 more
wiley   +1 more source

A Mussel‐Inspired Bioadhesive Patch to Selectively Kill Glioblastoma Cells

open access: yesAdvanced Science, EarlyView.
An innovative mussel‐inspired bioadhesive patch has been developed for post‐surgical glioblastoma treatment. The patch, which adheres strongly in biological environments, releases a localized treatment. This treatment, acting via reactive oxygen species, shows specific toxicity to glioblastoma cells.
Jose Bolaños‐Cardet   +5 more
wiley   +1 more source

Distribution and shared evolutionary history of the Fumonisin and AAL toxin biosynthetic gene clusters. [PDF]

open access: yesBMC Genomics
Proctor RH   +10 more
europepmc   +1 more source

Flipping the Switch: MeCP2‐Mediated Lactylation Rewires Microglial Metabolism and Inflammation via the HK2/mTOR Axis in Poststroke Neuroinflammation

open access: yesAdvanced Science, EarlyView.
Stroke‐induced lactate accumulation promotes p300‐mediated lactylation of methyl‐CpG binding protein 2 (MeCP2) at lysine 210, which reprograms microglial metabolism toward glycolysis and activates the hexokinase 2 (HK2)/mTOR axis. This cascade promotes proinflammatory responses and impairs neurofunctional outcomes.
Zengyu Zhang   +12 more
wiley   +1 more source

Usability of CHA<sub>2</sub>DS<sub>2</sub>VASC score in predicting the effectiveness and safety of pharmacological cardioversion - data from the multicenter cardioversion with intravenous ANTazoline study. [PDF]

open access: yesFront Cardiovasc Med
Krzowski B   +17 more
europepmc   +1 more source

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