Results 51 to 60 of about 222,062 (356)
Advanced Functional Materials, EarlyView.We present a novel proteolysis‐targeting chimera (PROTAC) system conjugated to lipoic acid gold nanoclusters (PLANC), designed to degrade pTau, regulate inflammatory signaling, and effectively traverse the blood‐brain barrier (BBB). PLANC degraded pTau at various phosphorylation sites, with mechanistic studies confirming proteasome‐mediated degradation
Sarah Nevins +9 more
wiley +1 more source
AdS5–Schwarzschild deformed black branes and hydrodynamic transport coefficients
Nuclear Physics B, 2020 A family of deformed AdS5–Schwarzschild black branes is here derived, employing the membrane paradigm of AdS/CFT. The solution of the Einstein–Hilbert action, with the Gibbons–Hawking term and a counter-term that eliminates eventual divergences, yields a
A.J. Ferreira–Martins +2 more
doaj +1 more source
Genotype data from 580 coho salmon individuals
, 2018 Genotype data from 580 coho salmon ...
José Manuel Yáñez (4346731) +7 more
core +1 more source
Advanced Healthcare Materials, EarlyView.Radiation‐induced hypothyroidism follows head and neck radiotherapy due to oxidative stress and inflammation. Electrospun polycaprolactone scaffolds containing adenosine have potential to modulate thyroid repair. Scaffolds enhance thyrocyte proliferation, antioxidant enzymes glutathione peroxidase and catalase, reduce senescence and apoptosis markers ...
Maria Heim +5 more
wiley +1 more source
, 2015 This file lists the 580 species in the 163 plots used in this ...
Xu, Han, Han Xu (68252)
core +1 more source
Design and Synthesis of Peptide‐Polyester Conjugates for Cell‐Mediated Scaffold Degradation
Advanced Healthcare Materials, EarlyView.This work describes polycaprolactone (PCL)‐based biomaterials engineered to degrade in response to cell‐secreted proteases. A fast‐degrading peptide (Fast) sequence is integrated into a PCL conjugate backbone to produce a biomaterial that is selectively degraded by multiple cell types compared to its scrambled control (ScrFast).
Korina Vida G. Sinad +7 more
wiley +1 more source
Results in Surfaces and InterfacesIn the current study the chemical constituents of Tabebuia heterophylla plant leaves extract (THLE) evaluated as corrosion inhibitor for low carbon steel (LCS) in 1 M HCl.
Geeta D. Pai +3 more
doaj +1 more source
Journal of Chemistry, 2013 In the present investigation, 1,2,4-triazole appended to pyrazoline and pyrazole rings (4a–g) using N-arylsydnone as synthon was prepared. The title compounds were subjected to Osiris property explorer for the oral bioavailability to analyze their drug ...
Tasneem Taj +3 more
doaj +1 more source
Copper–Collagen Interactions Regulate the Mechanical and Invasive Properties of Tumor Spheroids
Advanced Healthcare Materials, EarlyView.Ionic copper is investigated as a modulator of tumor spheroid growth and invasiveness in a 3D microfluidic glioblastoma model. Copper exposure alters metabolic activity, cytoskeletal organization, protrusion dynamics, and EMT‐related phenotypes in a dose‐ and timing‐dependent manner, revealing how copper bioavailability shapes tumor aggressiveness ...
Paula Guerrero‐López +5 more
wiley +1 more source
Biochemistry Research International, 2010 Ophthalmic mycoses caused by infectious fungi are being recognized as a serious concern since they lead to total blindness. Cephalosporium is one amongst several opportunistic fungal species implicated in ophthalmic infections leading to mycotic ...
Nagaraja N. Nagre +7 more
doaj +1 more source