Nicotine Reprograms Aging‐Related Metabolism and Protects Against Motor Decline in Mice
Long‐term oral nicotine intake protects against age‐related motor decline in mice without eliciting systemic toxicity. Integrated multi‐organ metabolomic profiling and longitudinal gut microbiota analyses reveal that nicotine induces coordinated remodeling of glycolipid and sphingolipid metabolism, enhances NAD⁺ bioavailability, and suppresses ceramide
Shuhui Jia+29 more
wiley +1 more source
The detection of toxic gases has gained significant attention in recent decades. Among various gas-sensing materials, metal oxide semiconductors (MOS) have emerged as highly promising due to their exceptional physical and chemical properties.
Julia Coelho Tagliaferro+5 more
doaj
Prognostic and predictive microRNA panels for heart failure patients with reduced or preserved ejection fraction: a meta-analysis of Kaplan-Meier-based individual patient data. [PDF]
Parvan R+9 more
europepmc +1 more source
Array-CGH fine mapping of minor and cryptic HR-CGH detected genomic imbalances in 80 out of 590 patients with abnormal development [PDF]
Helle Lybæk+5 more
openalex +1 more source
Mechanical Forces Guide Axon Growth through the Nigrostriatal Pathway in an Organotypic Model
Nano‐pulling is a magnetic nanoparticle‐based technology for guiding and promoting the axon growth of induced pluripotent stem cell‐derived dopaminergic neurospheres in vitro or neural progenitors transplanted in the brain tissue. Fine control of axon guidance is essential for reconstructing neural networks and restoring functional connectivity in the ...
Sara De Vincentiis+7 more
wiley +1 more source
Roles of MARCKSL1, MCM6, RFC4, and PLAU genes in esophageal cancer and their association with radiotherapy response. [PDF]
Zeng B+6 more
europepmc +1 more source
Erratum: Array-CGH fine mapping of minor and cryptic HR-CGH detected genomic imbalances in 80 out of 590 patients with abnormal development [PDF]
Helle Lybæk+5 more
openalex +1 more source
m6A modification stabilizes Slc15a3 mRNA in macrophages, activating the SLC15A3‐TASL‐IRF5 axis and promoting psoriatic inflammation. Abstract Impaired N6‐methyladenosine (m6A) modification has been implicated in regulating various inflammatory diseases, but its role in psoriasis remains unclear.
Tao Huang+13 more
wiley +1 more source
Distance travelled in the six-minute walk test in patients with chronic obstructive pulmonary disease as a predictor of mortality. [PDF]
Dourado IM+9 more
europepmc +1 more source