Results 211 to 220 of about 1,350,327 (326)

TREM2‐Mediated Cholesterol Efflux in Macrophages Inhibits Anti‐Tumor Immunity via Limitation of CD4+ T and NK Cells

Advanced Science, EarlyView.
Impaired anti‐tumor immunity is mediated by TREM2 + macrophages in non‐small cell lung cancer. TREM2 + macrophages prevent anti‐tumor immunity depending on the limitation of CD4 + T and NK cells. TREM2 promotes cholesterol efflux via ABCA1 to limit the production of CX3CL1 in macrophages.
Yunhan Wang, Weina Yu, Xinxin Wang, Qitai Zhao, Qingyang Lei, Aitian Li, Shasha Liu, Tian Wang, Li Yang, Yi Zhang   +9 more
wiley   +1 more source

#590 Inhibition of Histone deacetylase 6 restores kidney fibrosis in a mouse model of unilateral ureteral obstruction [PDF]

Ting‐Yu Wu, Hong-Mou Shih, Shuei‐Liong Lin   +2 more
openalex   +1 more source

590. SuperCD Enables Low Dose 5-FC Application for Effective Suicide Gene Therapy in a Rat Hepatoma Model Both In Vitro and In Vivo [PDF]

, 2004

openalex   +1 more source

Cold Atmospheric Plasma‐Activated In Situ Hydrogel Induces Hair Regeneration Via Immune Microenvironment Remodeling

Advanced Science, EarlyView.
A cold atmospheric plasma‐activated in situ hydrogel (CAPgel/IL2) delivers reactive oxygen species and interleukin‐2 to modulate the hair follicle immune microenvironment, enhancing regulatory T‐cell expansion, dermal papilla cell proliferation, and the telogen‐to‐anagen transition for robust hair regeneration.
Jung Suk Kim, Junho Byun, Jaehyun Choi, Dongun Jin, Qiaoyun Li, Jaiwoo Lee, Han‐Gon Choi, Yu‐Kyoung Oh   +7 more
wiley   +1 more source

590 Low level urine arsenic concentration and obstructive pulmonary disease among u.s. workers [PDF]

, 2018
ED Amster, David C. Christiani
openalex   +1 more source

Comment on acp-2022-590

, 2022
Xie, Fei, Su, Yue, Tian, Yongli, Shi, Yanju, Zhou, Xingjun, Wang, Peng, Yu, Ruihong, Wang, Wei, He, Jiang, Xin, Jinyuan, Lü, Changwei   +10 more
openalex   +1 more source

PBRM1 Deficiency Reshapes an Immune Suppressive Microenvironment Through Epigenetic Tuning of PBRM1‐KDM5C‐IL6 Axis in ccRCC

Advanced Science, EarlyView.
PBRM1 ranks as the second most commonly mutated gene in ccRCC. This study reveals that PBRM1 loss promotes an immunosuppressive microenvironment by elevating M2 TAMs via the KDM5C–IL‐6 axis. These M2 TAMs, along with CAFs, form a barrier that excludes CD8+ T cells. Targeting IL‐6 synergizes with anti‐PD1 therapy, offering a promising strategy for PBRM1‐
Wenjiao Xia, Hongru Wang, Yu Dong, Zitong Yang, Yiyang Zhou, Zhinan Xia, Qinchen Li, Liangliang Ren, Yichun Zheng, Junliang Yan, Dongmei Ma, Zhi Chen, Xingang Cui, Guixin Zhu, Cheng Zhang   +14 more
wiley   +1 more source

TGF-β2/OPTN/FOXC1/<i>miR-200</i> axis regulates actin dynamics in human trabecular meshwork cells. [PDF]

BBA Adv
Sugali CK, Gajula NN, Chava S, Reddy ABM.   +3 more
europepmc   +1 more source

Development of 590-MPa Class High Tensile Strength Steel with Superior HAZ Toughness by Copper Precipitation Hardening.

, 1994
Yukio TOMITA, Toshiaki Haze, Naoki Saito, Takeshi Tsuzuki, Yoshikuni TOKUNAGA, Kentaro Okamoto   +5 more
openalex   +2 more sources

Visible Light‐Activated ZnO@CuO Coaxial Nanofibers Enhance Infected Skin Wound Healing Through Construction of p‐n Heterojunctions

Advanced Science, EarlyView.
Coaxial ZnO@CuO nanofibers activated by visible light generate ROS through enhanced photocatalytic reactions driven by improved electron hole separation in the heterojunction. This strategy enables rapid antimicrobial activity and early infection control, thereby promoting the healing of MRSA infected and diabetic wounds with biosafe and easily ...
Pengrui Dang, Han Zhao, Chenguang Zhang, Jiechen Wang, Fangyu Zhu, Qinqiu Zhong, Wenyi Zeng, Xinyuan Wang, Yumin Chen, Xu Yan, Xuliang Deng, Wenwen Liu   +11 more
wiley   +1 more source