NOL6, a new founding oncogene in human prostate cancer and targeted by miR-590-3p
Cytotechnology (Dordrecht), 2020 Degang Dong +3 more
semanticscholar +1 more source
A Complementarity‐Based Approach to De Novo Binder Design
Advanced Science, EarlyView.A novel method for surface complementarity detection (HECTOR) enables highly efficient docking and design of protein interfaces. Applied to therapeutically relevant targets, this method yields de novo binders with potent antagonistic activity. As a first‐principles approach, HECTOR offers a training‐free solution to the binder design problem and is ...
Kateryna Maksymenko +17 more
wiley +1 more source
Optimizing resazurin-based viability assays for P-MSC/TER308 cell line to enhance results reliability. [PDF]
BMC Res NotesPetiti J, Revel L, Divieto C.
europepmc +1 more source
Statistical Language Models for Information Retrieval ChengXiang Zhai University of Illinois at Urbana Champaign Morgan & Claypool (Synthesis Lectures on Human Language Technologies, edited by Graeme Hirst), volume 1, 2008; xiii+125 pp, Princeton, NJ; paperbound, ISBN 978-1-59829-590-0, $40.00; ebook, ISBN 978-1-59829-591-7, $30.00 or by subscription [PDF]
, 2010 Éric Gaussier
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Advanced Science, EarlyView.Mechanical stress activates PIEZO1 in vertebral growth plate chondrocytes, triggering ferroptosis through direct binding and inhibition of GPX4. This axis promotes lipid peroxidation and pathological ossification, accelerating spinal deformities. Clinical and genetic evidence (Piezo1‐cKO) confirms its role in scoliosis progression.
Fei Chen +14 more
wiley +1 more source
Forty-year hydropower generation reanalysis for Conterminous United States. [PDF]
Sci DataTurner SWD, Singh D, Hansen C, Kao SC.
europepmc +1 more source
Antineoplastic Agents. 590. X-ray Crystal Structure of Dolastatin 16 and Syntheses of the Dolamethylleuine and Dolaphenvaline Units [PDF]
, 2011 George R. Pettit +7 more
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Advanced Science, EarlyView.By engineering bifunctional nitrogen‐dislocation interactions, this work constructs a heterogeneous lamellar structure with N‐rich low‐angle boundaries and coherent nanotwinned martensites, enabling ultrahigh yield/tensile strength (1532/1869 MPa) and activating massive
Chongle Zhang +5 more
wiley +1 more source
Correction: A Yin-Yang 1/miR-30a regulatory circuit modulates autophagy in pancreatic cancer cells. [PDF]
J Transl MedYang C +8 more
europepmc +1 more source
Advanced Science, EarlyView.HINT3 expression declines after myocardial ischemia‐reperfusion injury. In male mice, loss of HINT3 worsens cardiac injury and mitochondrial dysfunction, while its overexpression is protective. HINT3 binds the mitochondrial enzyme succinate dehydrogenase (SDHA) and prevents its deacetylation by histone deacetylase 1 (HDAC1), reducing succinate ...
Jiabin Yu +7 more
wiley +1 more source