Results 51 to 60 of about 336,410 (279)

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

open access: yesFEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima   +8 more
wiley   +1 more source

Security of Topology Discovery Service in SDN: Vulnerabilities and Countermeasures

open access: yesIEEE Open Journal of the Communications Society
Software-Defined Network (SDN) controller needs comprehensive visibility of the whole network to provide effective routing and forwarding decisions in the data layer.
Sanaz Soltani   +3 more
doaj   +1 more source

GR-TR, Extended Sensors, Extended sensors for assisted border-crossing

open access: yes, 2022
Use Case Category: Extended Sensors User Story: Extended sensors for assisted border-crossing Location: Greece - Turkey (GR-TR) cross-border corridor According to 3GPP TS 22.186 R16, Extended Sensors “enable the exchange of raw or processed data ...
5G-MOBIX
core   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu   +21 more
wiley   +1 more source

Energy Beamforming for MIMO WIPT Relaying With Arbitrary Correlation

open access: yesIEEE Access, 2018
This paper investigates the negative impact of spatial fading correlation in multiple-input multiple-output relaying systems on the performance of energy beamforming.
Ahmed Almradi, Pei Xiao
doaj   +1 more source

Longitudinal Assessment of Biomarkers in ALS: Discriminative Biomarkers for Disease Progression and Survival

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the association and discriminative performance of serum biomarkers with clinical disease progression and survival in patients with amyotrophic lateral sclerosis (ALS). Methods This retrospective study, conducted at Houston Methodist Hospital, Houston, TX, used longitudinal serum samples collected between January 2018 and ...
David R. Beers   +7 more
wiley   +1 more source

Optimizing Near-Field XL-MIMO Communications: Advanced Feedback Framework for CSI

open access: yesIEEE Access
With the successful deployment of fifth-generation (5G) systems, both industry and academia anticipate the evolution of 6G systems to meet future data-intensive needs.
Sourav Mukherjee   +2 more
doaj   +1 more source

Filtered OFDM: An Insight Into Intrinsic In-Band Interference and Filter Frequency Response Selectivity

open access: yesIEEE Access, 2020
The future mobile networks will face challenges in support of heterogeneous services over a unified physical layer, calling for a waveform with good frequency localization. Filtered orthogonal frequency division multiplexing (f-OFDM), as a representative
Juquan Mao   +3 more
doaj   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

Caterpillar RLNC With Feedback (CRLNC-FB): Reducing Delay in Selective Repeat ARQ Through Coding

open access: yesIEEE Access, 2018
Wireless networks typically employ some form of forward error correction (FEC) coding and some automatic repeat request (ARQ) protocol to ensure reliable data transmission over lossy channels.
Frank Gabriel   +4 more
doaj   +1 more source

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