Results 161 to 170 of about 5,346 (217)

Engineering Immunoregenerative Therapy via an Immunomodulatory Binary Pharmacology Hydrogel Depot for Prolonged Allograft Survival

Advanced Science, EarlyView.
An immunomodulatory hydrogel (iGEL) forms spontaneously upon subcutaneous injection, acting as a tissue‐adhesive depot. It releases anti‐rejection and regenerative agents in response to inflammation, suppressing T‐cell activity, promoting vascular repair, and restoring allograft function without systemic immunosuppression.
Ning Wang, Ruiqi Sun, Yang Fu, Zhonghan Wu, Xinyu Tong, Hong Tang, Wentao Zhao, Zhi Liang, Jintao Zheng, Yanan Guan, Ke Zhou, Penghong Song, Shusen Zheng, Hangxiang Wang, Haiyang Xie   +14 more
wiley   +1 more source

FGF13 Deficiency Ameliorates Paclitaxel‐Induced Neuropathic Pain by Inhibiting VASH1‐Mediated Microtubule Detyrosination to Promote Mitophagy

Advanced Science, EarlyView.
FGF13 is upregulated in DRG neurons of PIPNP model mice. DRG neuron‐specific knockout of FGF13 ameliorates PIPNP symptoms. Mechanistically, FGF13 potentiates microtubule detyrosination by promoting VASH1 binding to microtubules. FGF13 knockout suppresses VASH1‐mediated microtubule detyrosination and promotes α‐tubulin tyrosination.
Yiming Dong, Yidan Wang, Simeng Lv, Zishan Dong, Kaixi Zhi, Xiuhua Guo, Xuyan Li, Ruoxi Yu, Yiyi Zhang, Siyuan Cheng, Chuan Wang   +10 more
wiley   +1 more source

Single‐Cell Dissection of Therapy‐Induced Remodeling Uncovers a Fibroblast‐Driven Immunosuppressive Niche and Targetable Vulnerabilities in Lethal Prostate Cancer

Advanced Science, EarlyView.
Single‐cell longitudinal profiling reveals that androgen‐deprivation therapy induces a DPT+ fibroblast‐complement axis that suppresses macrophage inflammation and drives CD8+ T cell exhaustion in prostate cancer. Concurrently, resistant epithelial subpopulations persist and engage TSPAN1‐ and NRXN1‐mediated programs promoting CRPC and neuroendocrine ...
Yang Chen, Dandan Dong, Jinling Liao, Naikai Liao, Mengqi Liu, Qin Zhang, Siting Chen, Qi Liu, Ying Lu, Tianyu Li, Chunlin Zou, Qiong Song, Qiuyan Wang, Jian Liang, Qiji Xie, Chengyang Li, Mengyun Wang, Jiwen Cheng, Zengnan Mo, Gong‐Hong Wei   +19 more
wiley   +1 more source

Wavy‐Interlocked Stretchable Triboelectric Nanogenerators Enhanced by Liquid Metal Microflowers for Self‐Powered Wearable Motion Monitoring

Advanced Science, EarlyView.
Schematic showing a stretchable triboelectric nanogenerator based on interlocked wavy architectures that uses EGaIn microflower‐embedded PVDF‐TrFE and Nylon‐6 nanofiber membranes. The multi‐petaled, electron‐rich EGaIn microflowers enhance interfacial polarization and capacitance, while the interlocked wavy architecture enlarges the effective contact ...
Qianqian Xu, Huimin Li, Hanmin Zeng, Yahui Meng, Yimeng He, Xinke Hu, Senfeng Zhao, Jianxun Zhang, Peiqiong Zhou, Kechao Zhou, Dou Zhang, Chris Bowen, Yan Zhang   +12 more
wiley   +1 more source

Chiral Nanoparticles Suppress Inflammatory Infiltration to Promote Extracellular Matrix Remodeling for Ectopia Lentis Therapy

Advanced Science, EarlyView.
L‐cysteine‐configured chiral polyurethane nanoparticles suppress ocular inflammation and reduce extracellular matrix (ECM) degradation in ectopia lentis by regulating macrophages polarization and inhibiting nuclear factor kappa B signaling pathway. By promoting zonular fiber‐associated protein restoration and tissue repair, this minimally invasive ...
Yinuo Wen, Yan Yang, Haihan Gao, Yan Liu, Xinyue Wang, Linghao Song, Ruohong Li, Ao Miao, Jie Xu, Zhennan Zhao, Dan Li, Shenjie Peng, Linzhao Li, Min Zhang, Yonghang Liu, Liren Wang, Tianhui Chen, Yongxiang Jiang   +17 more
wiley   +1 more source

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5G‐Hander: A network service for handover detection in 5G networks

Internet Technology Letters, 2019
In the next Fifth Generation (5G) networks, Telco Operators will assign network slices to their users and will guarantee very stringent requirements even in mobility. In this context, detecting handover events will be challenging in order to design management and orchestration policies allowing resource allocation and network slice assignment ...
Christian Grasso, Giovanni Schembra
openaire   +1 more source

Network Virtualization and Survivability of 5G Networks

Journal of Network and Systems Management, 2020
5G networks are slated to provide a wide range of services. A critical need in service delivery in 5G networks is its resilience. In this work, we present a 5G network architecture with network virtualization in a multiple provider setting for network resilience that uses a self-organizing ad hoc network among the gNBs (macrosites).
Rohit Abhishek, David Tipper, Deep Medhi
openaire   +1 more source

Cognitive Robotics on 5G Networks

ACM Transactions on Internet Technology, 2021
Emotional cognitive ability is a key technical indicator to measure the friendliness of interaction. Therefore, this research aims to explore robots with human emotion cognitively. By discussing the prospects of 5G technology and cognitive robots, the main direction of the study is cognitive robots.
Zhihan Lv, Liang Qiao 0003, Qingjun Wang
openaire   +1 more source

5G Networks

2019
Mobile communication witnesses a new generation after every 10 years. Following the same trend, the roll out of next generation called 5G network is anticipated by 2020. In this chapter, a critical review of enabling technologies and research issues of 5G network is provided.
Noman Islam, Ainuddin Wahid Abdul Wahab
openaire   +2 more sources

Networks and devices for the 5G era

IEEE Communications Magazine, 2014
Mobile services based on 4G LTE services are steadily expanding across global markets, providing subscribers with the type of responsive Internet browsing experience that previously was only possible on wired broadband connections. With more than 200 commercial LTE networks in operation as of August 2013 [1], LTE subscriptions are expected to exceed 1 ...
Boyd Bangerter, Shilpa Talwar, Reza Arefi, Ken Stewart   +3 more
openaire   +1 more source