Results 41 to 50 of about 1,034 (192)

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni   +19 more
wiley   +1 more source

The SDG Nexus in Practice: Integrated Water Resources Management as a Pathway for Sustainability in Central Asia [PDF]

open access: yesE3S Web of Conferences
Water resources in arid Central Asia face pressure from climate change, Soviet-era infrastructure, and transboundary governance challenges. This study examines integration of SDG 6 (Clean Water), SDG 13 (Climate Action), and SDG 15 (Life on Land) within ...
Mirkhamidova Sevara M.   +5 more
doaj   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit   +11 more
wiley   +1 more source

Cumulative Social Disadvantage and Disease Activity in Juvenile Idiopathic Arthritis: A Childhood Arthritis and Rheumatology Research Alliance Registry Study

open access: yesArthritis Care &Research, EarlyView.
Objective Social determinants of health (SDOH) contribute to juvenile idiopathic arthritis (JIA) disparities, but most studies have assessed SDOH independently rather than cumulatively across individual, family, and neighborhood levels. Using a socioecological framework, we investigated the relationship among cumulative social disadvantage ...
William Daniel Soulsby   +448 more
wiley   +1 more source

A scoping review of the links between early childhood caries and clean water and sanitation: the Sustainable Development Goal 6

open access: yesBMC Oral Health
Introduction The United Nation’s Sustainable Development Goal (SDG) 6 calls for universal access to clean water, sanitation and hygiene (WASH), which are crucial elements of health and well-being and fundamental for a life in dignity.
Yasmi O. Crystal   +17 more
doaj   +1 more source

Analisis Kondisi Eksisting Jaringan Pipa Distribusi Air Bersih Kelurahan Simpang Rumbio, PDAM Kota Solok

open access: yesJurnal Serambi Engineering, 2019
This research is intended to determine the hydraulic conditions of the clean water distribution network in Simpang Rumbio Village by Solok City PDAM, in order to resolve water problems that often do not flow in the city border area and its surroundings ...
Ridwan Ridwan
doaj   +1 more source

Thermodynamic Pathways of Nonequilibrium Solidification in Wire‐Arc Additive Manufacturing Fe‐Based Multicomponent Alloy Structures

open access: yesAdvanced Engineering Materials, EarlyView.
Geometry‐driven thermal behavior in wire‐arc additive manufacturing (WAAM) influences microstructural evolution during nonequilibrium solidification of a chemically complex Fe–Cr–Nb–W–Mo–C nanocomposite system. By comparing different deposits configurations, distinct entropy–cooling rate correlations, segregation, and carbide evolution are revealed ...
Blanca Palacios   +5 more
wiley   +1 more source

Air‐Pressure–Actuated Vibroacoustic Metamaterial With Tunable Bandgap: Design, Modeling, and Characterization

open access: yesAdvanced Engineering Materials, EarlyView.
This article presents the design, modeling, and characterization of air‐pressure–actuated programmable vibroacoustic metamaterials (PVAMM). The study focuses on leveraging air pressure to dynamically tune resonance frequencies for effective noise attenuation.
William Kaal   +2 more
wiley   +1 more source

Assessing Rural Communities in Central and East Africa: How to Provide Clean Water and Sanitation by 2030

open access: yesEnvironmental Health Insights
Introduction: The provision of clean drinking water and proper sanitation is essential for public health, particularly in rural areas with limited resources.
Birhanu Chalchisa Werku   +1 more
doaj   +1 more source

Gaza and the collapse of global health ethics: the forgotten mandate of Sustainable Development Goals

open access: yesInternational Journal of Infectious Diseases
The Sustainable Development Goals (SDGs) articulate a global consensus to end hunger, secure health, and ensure access to safe water for all by 2030. However, in Gaza, the worlds’ failure to uphold SDG 2 (Zero Hunger), SDG 3 (Good Health and Well-being),
Thirumalaisamy P Velavan   +2 more
doaj   +1 more source

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