Results 61 to 70 of about 2,196,749 (339)
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu+17 more
wiley +1 more source
Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield+3 more
wiley +1 more source
Problems with clean water in coastal areas alongside an increase in population and community economic activities have diversified community activities. Coastal settlements bordering the high seas are characterized as arid areas with a lack of clean water.
Nur Khafifah Rusni+3 more
doaj +1 more source
ir bersih merupakan kebutuhan dasar untuk kehidupan manusia. Demikian pula aktivitas kehidupan di pulau Nusa Ceningan dan Lembongan membutuhkan air bersih.
Made Suarda, I Gusti Komang Dwijana
doaj +1 more source
What do Indian children drink when they do not receive water?:statistical analysis of water and alternative beverage consumption from the 2005-2006 Indian National Family Health Survey [PDF]
BACKGROUND: Over 1.2 billion people lack access to clean water. However, little is known about what children drink when there is no clean water. We investigated the prevalence of receiving no water and what Indian children drink instead.
Basu, Sanjay+5 more
core +3 more sources
The 17 Sustainable Development Goals (SDGs) underpinned by 169 targets presents national governments with huge challenges for implementation. We developed a proposal for a National Blueprint Framework (NBF) with 24 water-related indicators, centered on ...
B. Essex, S. Koop, C. V. Leeuwen
semanticscholar +1 more source
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu+11 more
wiley +1 more source
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
UN Sustainable Development Goal 6 aims to achieve clean water for all. Access to clean water is a basic human right but can be costly and challenging.
Lucy Crockford
doaj +1 more source
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon+13 more
wiley +1 more source