Results 61 to 70 of about 1,250,127 (301)

Respiratory complex I‐mediated NAD+ regeneration regulates cancer cell proliferation through the transcriptional and translational control of p21Cip1 expression by SIRT3 and SIRT7

Molecular Oncology, EarlyView.
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi, Kazunori Mori, Hidetsugu Nakagawa, Momoko Uchida, Fumihiro Ishikawa, Motoko Shibanuma   +5 more
wiley   +1 more source

The Effects of Bitter Kola Supplemented Diet on Hepatotoxicity of Mercury in Wistar Rats

Journal of Applied Sciences and Environmental Management, 2010
The effect of bitter kola on the hepatotoxicity following mercury poisoning (mercuric chloride solution of 10ppm) was investigated in rats for a duration of six weeks. Thirty (30) acclimatized Wistar rats were divided into five groups(n=6).Group I served
C Nwokocha, D Ejebe, E Nwangwa, N Ekene, R Akonoghrere, J Ukwu   +5 more
doaj   +1 more source

Thermal decomposition of hydrated graphite oxide: A computational study [PDF]

arXiv, 2022
We study the behavior of hydrated graphite oxide (GO) at high temperatures using thermally accelerated molecular dynamics simulations based on ab initio density functional theory. Our results suggest that GO, a viable candidate for water treatment and desalination membranes, is more heat resilient than currently used organic materials.
arxiv  

Synergies and Trade-offs among Sustainable Development Goals: The Case of Spain

Sustainability, 2020
The United Nations plans have marked global sustainable development for more than two decades. Most of the developed and developing countries have adopted these plans to achieve the Agenda 2030, currently formed by the 17 Sustainable Development Goals ...
Carlos de Miguel Ramos, Rafael Laurenti
semanticscholar   +1 more source

Germline variants in CDKN2A wild‐type melanoma prone families

Molecular Oncology, EarlyView.
Among melanoma‐prone families, wild‐type for CDKN2A and CDK4, some have pathogenic variants in genes not usually linked to melanoma. Furthermore, rare XP‐related variants and variants in MC1R are enriched in such families. Germline pathogenic variants in CDKN2A are well established as an underlying cause of familial malignant melanoma. While pathogenic
Gjertrud T. Iversen, Marie Loeng, Amalie Lund Holth, Per E. Lønning, Jürgen Geisler, Stian Knappskog   +5 more
wiley   +1 more source

A brief account of the 2030 agenda and its implications for Brazil and the Amazon Region in achieving Sustainable Development Goal 6: Clean Water and Sanitation [PDF]

, 2022
Simone Bessa de Almeida, Edson Pablo da Silva   +1 more
openalex   +1 more source

Tropical Medicine and International Health and the 2030 Agenda for Sustainable Development

Tropical medicine & international health, 2020
Sustainable Development Goals (SDGs) SDG 1 (no poverty), SDG 2 (zero hunger), SDG 3 (good health and well-being), SDG 4 (quality education), SDG 5 (gender equality), SDG 6 (clean water and sanitation), SDG 7 (affordable and clean energy), SDG 8 (decent ...
Anaïs Galli, Andrea Leuenberger, Dominik Dietler, H. Fletcher, T. Junghanss, J. Utzinger   +5 more
semanticscholar   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

Progressive Cleaning and Mining of Uncertain Smart Water Meter Data [PDF]

arXiv, 2020
Several municipalities have recently installed wireless 'smart' water meters that allow functionalities such as demand response, leak alerts, identification of characteristic demand patterns, and detailed consumption analysis. To achieve these benefits, the meter data needs to be error-free, which is not necessarily available in practice, due to ...
arxiv  

Improved Self-cleaning Properties of an Efficient and Easy to Scale up TiO2 Thin Films Prepared by Adsorptive Self-Assembly [PDF]

, 2019
Transparent titania coatings have self-cleaning and anti-reflection properties (AR) that are of great importance to minimize soiling effect on photovoltaic modules. In this work, TiO2 nanocolloids prepared by polyol reduction method were successfully used as coating thin films onto borosilicate glass substrates via adsorptive self-assembly process. The
arxiv   +1 more source