Results 191 to 200 of about 1,327,455 (347)

Salvage esophagectomy for unresectable locally advanced esophageal squamous cell carcinoma: Significant or not?

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
Abstract We reviewed the current status and perspectives on salvage esophagectomy for initially unresectable locally advanced esophageal squamous cell carcinoma (ESCC) in the era of minimally invasive surgery and immunotherapy. Although the standard treatment for these patients is definitive chemoradiotherapy (CRT), the complete response rate to CRT ...
Hiroshi Saeki   +4 more
wiley   +1 more source

Prognostic Impact of Bone Mineral Density Reduction During Neoadjuvant Chemotherapy (NAC) in Patients Undergoing NAC Followed by Esophagectomy for Esophageal Cancer

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
The association between BMD reduction during NAC and the worse prognosis remains unknown, although NAC followed by esophagectomy is a standard treatment for advanced ESCC. This study appeared that BMD massive reduction was an independent prognostic factor on OS (HR, 3.30; 95% confidence interval [CI], 1.69–6.55) and RFS (HR, 2.08; 95% CI, 1.19–3.63 ...
Kazuhide Sato   +11 more
wiley   +1 more source

SAR exploration of the non‐imidazole histamine H3 receptor ligand ZEL‐H16 reveals potent inverse agonism

open access: yesArchiv der Pharmazie, Volume 356, Issue 1, January 2023., 2023
ZEL‐H16 (1) has been disclosed to be a high‐affinity non‐imidazole H3R (partial) agonist. However, it was found that 1 acts as an inverse agonist for Gαi in various assays. Concise structure–activity relationship studies, molecular pharmacology, and docking were used to shed more light on the properties of 1.
Gábor Wágner   +12 more
wiley   +1 more source

Establishment and genomic profiling of cholangiocarcinoma cells with functional characterization. [PDF]

open access: yesSci Rep
Jaidee R   +20 more
europepmc   +1 more source

Single nucleotide polymorphisms in the CDH18 gene affect growth traits in Hu sheep

open access: yesAnimal Research and One Health, EarlyView., 2023
Abstract Growth traits are critical economic traits in sheep. Genetic polymorphism has a great influence on the improvement of sheep traits. The aim of this study was to analyze the effect of cadherin 18 (CDH18) gene polymorphisms on growth traits in Hu sheep.
Tianyi Liu   +5 more
wiley   +1 more source

Heavy‐Atom‐Induced Narrow Emission in Chalcogen‐Coordinating Lanthanide Cerium(III) Complexes

open access: yesAggregate, EarlyView.
A novel heavy‐atom‐induced narrow emission is observed in luminescent Ce(III) complexes by adopting imidodiphosphinate ligand with different chalcogen‐coordinating sites such as O, S, Se, and Te. In the heaviest Te‐coordinating complex, the full width at half maxima is only 42 nm, which is the narrowest emission band of Ce(III).
Jiayin Zheng   +9 more
wiley   +1 more source

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