Results 201 to 210 of about 1,437,575 (283)

Letter Circular 610:

, 1940
openaire   +1 more source

Population pharmacokinetics and dose–response relationships of mitoxantrone in children with acute myeloid leukaemia

British Journal of Clinical Pharmacology, EarlyView.
Background Information on mitoxantrone pharmacokinetics in children is lacking and reduced dosing regimens applied to infants are supported by limited scientific rationale. The current study characterized mitoxantrone pharmacokinetics in a childhood acute myeloid leukaemia patient population and provides a data‐informed assessment of dosing.
Andrew M. Brandon, Hinke Huisman‐Siebinga, Shelby Barnett, Paul Wetherell, Pamela Kearns, Brenda Gibson, Nicholas Heaney, Owen Smith, André Baruchel, Arnaud Petit, Andrew Moore, Kayode Ogungbenro, Alwin D. R. Huitema, Gareth J. Veal   +13 more
wiley   +1 more source

Kinesin-1 is highly flexible and adopts an open conformation in the absence of cargo. [PDF]

iScience
Smith ER, Turner ED, Abdelhamid MAS, Craggs TD, Twelvetrees AE.   +4 more
europepmc   +1 more source

The quantitative impact of metabolism‐inhibiting drugs on the occurrence of adverse drug reactions—A backward selection approach

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim The quantitative effect of several inhibitory drugs on the development of adverse drug reactions (ADRs) is currently difficult to estimate. Our aim was to identify metabolic pathways, which, when inhibited, increase the risk for certain ADRs, and to use this system to consider comedication at individual level. Methods Data of a prospective
Judith Berres, Justyna Wozniak, Hannah Fölsch, Anja Knueppel‐Ruppert, Verena Graeff, Andrea Kriegisch‐Stumpf, Harald Dormann, Julia C. Stingl, Katja S. Just   +8 more
wiley   +1 more source

Paternal postpartum depression and its associated factors among partners of postpartum women at Dessie Town, Northeast Ethiopia, 2023: a community-based cross-sectional study. [PDF]

BMJ Open
Assefa A, Workie A, Assefaw M, Abate AB.
europepmc   +1 more source

Heraclius (610-641); Alexandria; 610 - 613; 12 Nummi; MIB III 199

Die Münzsammlung des Instituts für Alte Geschichte und Altertumskunde der Universität Graz umfasst fast 4000 antike Münzen. Die Sammlungsbereiche erstrecken sich vom klassischen Griechenland über bedeutsame Bestände hellenistischer und keltischer Münzen bis hin zu völkerwanderungszeitlichen und byzantinischen Objekten.
openaire   +1 more source

Generative AI, ESG Sensemaking, and Environmental Performance: an OIPT Perspective

Business Strategy and the Environment, EarlyView.
ABSTRACT Despite growing enthusiasm for generative artificial intelligence (GenAI) in sustainability management, it remains unclear how such technologies translate vast ESG information into meaningful environmental outcomes. This study addresses this gap by investigating how ESG sensemaking capability mediates the relationship between GenAI integration
Surajit Bag, Gautam Srivastava, Susmi Routray, Andrea Chiarini   +3 more
wiley   +1 more source

Results and indications changes by prenatal diagnosis of 3,458 pregnant women: a 10-year retrospective study. [PDF]

Ann Med
Wang C, Zhang H, Liu Y, Wang R, Li Q, Zhang X, Huang X, Zhang Y, Liu M.   +8 more
europepmc   +1 more source

Effect of cell retention techniques in Komagataella phaffii lab‐scale continuous processes

Biotechnology Progress, EarlyView.
Abstract Perfusion technologies play a growing role in the implementation of continuous processes for biotherapeutics production in mammalian‐based manufacturing. However, their application to alternative production hosts is limited. Cell retention systems are of key importance for the efficiency of perfusion bioreactors.
Marina Y. Linova, Satish K. Kodiripaka, Edite Martins, Sobhana A. Sripada, Stefano Menegatti, John M. Woodley   +5 more
wiley   +1 more source

Results of Multigene Panel Testing, Including <i>PKD1</i>, in >1,200 Patients With Cystic Kidney Disease: A Retrospective Analysis. [PDF]

Kidney Med
Tapper EE, Huusko JM, Scocchia AM, Gall K, Roberts MB, Bernal-Quirós M, Valo S, Saarinen I, Rantanen M, Pietila T, Gentile M, Koskinen L, Kumar MM, Myllykangas S, Koskenvuo J.   +14 more
europepmc   +1 more source