Results 221 to 230 of about 1,472,811 (373)

Targeted Degradation of eEF2K by a Structure‐Guided PROTAC Strategy for the Treatment of Triple‐Negative Breast Cancer

open access: yesAdvanced Science, EarlyView.
This study developed an eEF2K‐targeting PROTAC, A6, that efficiently degrades eEF2K in TNBC cells, inhibiting tumor growth in vitro and in vivo. To enhance tumor‐specific delivery, we engineered A6@ZIF‐8, a pH‐sensitive nanocarrier, which improved drug accumulation at tumor sites, offering a promising therapeutic strategy for TNBC through targeted ...
Shijun Cao   +10 more
wiley   +1 more source

Site 610

open access: yes, 1987
openaire   +1 more source

A Comparison of Bulk with Micro‐Volume Elemental Values for NIST SRM 610 and NIST SRM 612 [PDF]

open access: hybrid
Nicholas Sharp   +7 more
openalex   +1 more source

All‐Optical Control of Bidirectional Polarization Switching in Ferroelectric Heterostructures for Neuromorphic and In‐Memory Computing

open access: yesAdvanced Science, EarlyView.
We propose an optical ferroelectric field‐effect transistor, composed of a MoS2/CIPS heterostructure, demonstrates the feasibility of all‐optical nonvolatile memory, neuromorphic computing, and logic‐in‐memory operations. The device exhibits reversible light‐controlled memory states, retina‐like synaptic plasticity, and wavelength‐selective ...
Jingjie Niu   +7 more
wiley   +1 more source

Plasmonic Metal-Phenolic Network Nanoprobes for Multiplex Dual-Mode Immunophenotyping. [PDF]

open access: yesNano Lett
González-Cabaleiro L   +8 more
europepmc   +1 more source

Designing Advanced Soft Magnetic Powder Cores with Ultralow Energy Loss by Combining Ultrasonic and Static Compaction

open access: yesAdvanced Science, EarlyView.
Increasing the density and homogeneity of soft magnetic composites are critical for achieving high power density and low core loss. This work proposes a novel strategy by combining ultrasonic‐assisted pressing and cold pressing. In this line, the density and permeability of magnetic core have been increased a lot, while the core loss is decreased ...
Xiaoying Huang   +15 more
wiley   +1 more source

Prevalence of Undiagnosed Risk Factors in Patients with First-Ever Ischemic Stroke Treated at MUHC: A Retrospective Analysis. [PDF]

open access: yesJ Pers Med
Althubait S   +8 more
europepmc   +1 more source

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