Results 21 to 30 of about 1,570,051 (283)

Circ_0015756 Aggravates Hepatocellular Carcinoma Development by Regulating FGFR1 via Sponging miR-610

Cancer Management and Research, 2020
Weisheng Guo,1 Lin Zhao,1 Guangya Wei,1 Peng Liu,1 Yu Zhang,1 Liran Fu2 1Department of Hepatobiliary Surgery, Henan Province Hospital of Traditional Chinese Medicine, The Second Affiliated Hospital of Henan University of Traditional Chinese Medicine ...
Guo W, Zhao L, Wei G, Liu P, Zhang Y, Fu L   +5 more
doaj  

Coevolution of the Features of the Dynamics of the Accelerator Pedal and Hyperparameters of the Classifier for Emergency Braking Detection

Actuators, 2018
We investigate the feasibility of inferring the intention of the human driver of road motor vehicles to apply emergency braking solely by analyzing the dynamics of lifting the accelerator pedal.
Albert Podusenko, Vsevolod Nikulin, Ivan Tanev, Katsunori Shimohara   +3 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Mechanical Performance and Durability of Concretes with Partial Replacement of Natural Aggregates by Construction and Demolition Waste

Waste
This study investigated the mechanical performance and durability of concretes produced with varying proportions of recycled coarse aggregate from construction and demolition waste (CDW), ranging from 0% to 100% replacement of natural coarse aggregate ...
Thamires Alves da Silveira, Rafaella dos Passos Nörnberg, Marcelo Subtil Santi, Renata Rabassa Morales, Alessandra Buss Tessaro, Hebert Luis Rosseto, Rafael de Avila Delucis, Guilherme Hoehr Trindade   +7 more
doaj   +1 more source

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

FEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson, Anja H. Schiemann, Evelyn Sattlegger   +2 more
wiley   +1 more source

Investigation of measurement method of saturation magnetization of iron core material using electromagnet

AIP Advances, 2018
This paper discusses a measurement method for saturation magnetizations of iron core materials using an electromagnet, which can apply an extremely large magnetic field strength to a specimen.
Takuya Shibataki, Yasuhito Takahashi, Koji Fujiwara   +2 more
doaj   +1 more source

Dactolisib outperforms Rapamycin in potentiating apoptosis induced by XPO1, Bcl‐2 and Mcl‐1 blockade in preclinical glioblastoma models

FEBS Open Bio, EarlyView.
The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao, Leonie Meyer, Madita Braun, Katharina Otte, Celine Bitter, Maite Pawlik, Hartmann Raifer, Frederik Helmprobst, Axel Pagenstecher, Hans Urban, Michael C. Burger, Michael W. Ronellenfitsch, Joachim P. Steinbach, Jarmila Jedelská, Shamim Bagheri, Behrooz H. Yousefi, Pietro Di Fazio, Markus Luster, Andreas H. Mahnken, Andreas Neubauer, Andreas Burchert, Christopher Nimsky, Jörg W. Bartsch, Tillmann Rusch   +23 more
wiley   +1 more source

Safety and Efficacy of GLP‐1 Receptor Agonists in Adults With Epilepsy, Obesity, and Type 2 Diabetes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Managing obesity in patients with epilepsy is complicated by the weight‐gaining properties of essential antiseizure medications (ASMs) such as valproate and pregabalin. We evaluated the safety and efficacy of initiating glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) in this population.
Hyoshin Son, Inyoung Hwang, Sang Won Lee, Yun Kim   +3 more
wiley   +1 more source

Spatiotemporal Patterns of 45-Day Precipitation in Rio Grande Do Sul State, Brazil: Implications for Adaptation to Climate Variation

Atmosphere
Understanding precipitation variability is essential for assessing climate dynamics and their impacts on agriculture, water resources, and infrastructure.
Luana Centeno Cecconello, Angela Maria de Arruda, André Becker Nunes, Tirzah Moreira Siqueira   +3 more
doaj   +1 more source

Clinical Validation of Artificial Intelligence (AI)‐based Cartilage Segmentation Predicting Knee Replacement

Arthritis Care &Research, Accepted Article.
Objective For cartilage morphology to serve as a scalable endpoint in clinical trials, analyses should be performed automatically without human interaction. To clinically validate artificial intelligence (AI)‐based analysis, we studied cartilage loss from MRI prior to knee replacement.
Felix Eckstein, David J. Hunter, C. Kent Kwoh, Wolfgang Wirth   +3 more
wiley   +1 more source