Results 51 to 60 of about 1,327,455 (347)

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source

The Effects of Speed on the Running Performance of a Small Two-Wheeled Lunar Rover

Aerospace
Small wheeled lunar rovers tend to dig into surfaces via wheel rotation, causing them to slip and get stuck on regolith. Additionally, reducing power consumption remains a longstanding challenge. This study created a small two-wheeled rover and conducted
Kimitaka Watanabe, Yamato Otani, Kazuto Tanaka   +2 more
doaj   +1 more source

Dialog filozofii z historią: zagadkowy wstęp do Historii powszechnej Teofilakta Simokatty

Vox Patrum, 2018
The paper seeks to propose an interpretation of Dialogue between History and Philosophy – prefatory to Simocattes’ History. In the author’s opinion, this brief text deprived of literary value, provides for Theophylactus’ peculiar attempt to justify his ...
Anna Kotłowska
doaj   +1 more source

Furniture Style Compatibility Estimation by Multi-Branch Deep Siamese Network

Mathematical and Computational Applications, 2022
As demands for understanding visual style among interior scenes increase, estimating style compatibility is becoming challenging. In particular, furniture styles are difficult to define due to their various elements, such as color and shape. As a result,
Ayumu Taisho, Keiko Ono, Erina Makihara, Naoya Ikushima, Sohei Yamakawa   +4 more
doaj   +1 more source

On subcellular distribution of the zinc finger 469 protein (ZNF469) and observed discrepancy in the localization of endogenous and overexpressed ZNF469

FEBS Open Bio, EarlyView.
ZNF469 regulates the expression of genes encoding extracellular matrix proteins. Endogenous ZNF469 is predominantly cytoplasmic, while in transfected cells, it forms aggregates reminiscent of biomolecular condensates, located mainly in the nucleus. These condensates exhibit overlapping staining with proteasomes and are also associated with the mitotic ...
Anne Elisabeth Christensen Mellgren, Ileana Cristea, Thomas Stevenson, Endy Spriet, Per Morten Knappskog, Stig Ove Bøe, Harald Kranz, Sushma N. Grellscheid, Eyvind Rødahl   +8 more
wiley   +1 more source

The Long Term Effects of a 12‐Session Community Exercise Program on Health Measures in Cancer Patients

Aging and Cancer, EarlyView.
ABSTRACT Purpose To assess the long‐term effects of a community cancer exercise program on quality of life, fatigue, weight, waist circumference, physical activity levels, lower extremity strength, body mass index (BMI), heart rate, and blood pressure, across non‐metastatic and metastatic patients.
Isaac Oppong, Roozbeh Naemi
wiley   +1 more source

The agent routering process of a dynamic distributed decision support system

Journal of Computer Science and Technology, 2001
When certain enterprise domain needs to make an unusual decision, it will probably require new kind of information. If the interaction model among domains cannot be defined because the decision scenarios are unpredictable, the system itself must search ...
Georgina S. Stegmayer Machado, María Laura Taverna, Omar Juan Alfredo Chiotti, María Rosa Galli   +3 more
doaj  

Effect of Soil Type on Running Performance of Small Lunar Rover

Aerospace
It is very easy for a small lunar rover to slip on the regolith of the lunar surface and become stuck. Previous studies have quantitatively evaluated the effects of wheel geometry, such as elliptical or eccentric wheels, on the performance of a rover ...
Kimitaka Watanabe, Tomoki Horiguchi, Kazuto Tanaka   +2 more
doaj   +1 more source

Development of PF-06671008, a Highly Potent Anti-P-cadherin/Anti-CD3 Bispecific DART Molecule with Extended Half-Life for the Treatment of Cancer

Antibodies, 2016
Bispecific antibodies offer a promising approach for the treatment of cancer but can be challenging to engineer and manufacture. Here we report the development of PF-06671008, an extended-half-life dual-affinity re-targeting (DART®) bispecific molecule ...
Adam R. Root, Wei Cao, Bilian Li, Peter LaPan, Caryl Meade, Jocelyn Sanford, Macy Jin, Cliona O’Sullivan, Emma Cummins, Matthew Lambert, Alfredo D. Sheehan, Weijun Ma, Scott Gatto, Kelvin Kerns, Khetemenee Lam, Aaron M. D’Antona, Lily Zhu, William A. Brady, Susan Benard, Amy King, Tao He, Lisa Racie, Maya Arai, Dianah Barrett, Wayne Stochaj, Edward R. LaVallie, James R. Apgar, Kristine Svenson, Lidia Mosyak, Yinhua Yang, Gurunadh R. Chichili, Liqin Liu, Hua Li, Steve Burke, Syd Johnson, Ralph Alderson, William J. J. Finlay, Laura Lin, Stéphane Olland, William Somers, Ezio Bonvini, Hans-Peter Gerber, Chad May, Paul A. Moore, Lioudmila Tchistiakova, Laird Bloom   +45 more
doaj   +1 more source

1701 + 610 - A QSO with a tidal tail

The Astronomical Journal, 1986
The paper presents deep CCD imaging of the X-ray-selected QSO 1701 + 610, which reveals the presence of a long-curved tail exceeding 80 kpc in length. The QSO has redshift 0.169, and lies in an absorption-line galaxy that has two secondary nuclei 2.7 and 5.9 arcsec from the central nucleus, on the side away from the tail.
M.M. De Roberts, P. Hickson, J. B. Hutchings   +2 more
openaire   +2 more sources