Results 51 to 60 of about 1,589,534 (227)

Single‐Molecule Imaging of Endogenous RNA Using a Miniaturized and Circularly Permuted CRISPR‐Cas13 Degron‐Masking System CDegSR

Advanced Science, EarlyView.
CDegSR, a new tool for imaging RNA at single molecule level in living cells was developed by researchers. Background noise was eliminated by protein engineering and making it degrade when not bound to its target. This allowed individual RNA molecules to be clearly imaged and tracked.
Shipeng Shao, Hongchen Zhang
wiley   +1 more source

Me and My New World: Effects of a School Based Social-Emotional Learning Program for Adolescents in Panama

Education Sciences, 2020
Gender inequalities still affect the health and well-being of young people worldwide. Given the apprehensions among government and educators in a conservative context like Panama to implement comprehensive sexual education, there is a need for other ...
Ana Belinda Araúz Ledezma, Karlijn Massar, Gerjo Kok   +2 more
doaj   +1 more source

Improving High‐Temperature Operational Stability of Inverted Perovskite Solar Cells Through MXene Heat‐Dissipating Layers

Advanced Science, EarlyView.
MeO‐2PACz‐functionalized MXene nanosheets create a thermally conductive buried interface in inverted perovskite solar cells. The interface improves heat spreading, suppresses defects and ion migration, and strengthens charge extraction, extending T80 at 65°C from 141 to 687 h while maintaining competitive efficiency.
Masoud Karimipour, Nil Monrós Oliveras, Zhenchuan Tian, Timm Swoboda, Francesco Salutari, Marianna Sledzinska, Maria Chiara Spadaro, Kenedy Tabah Tanko, Javier Rodríguez‐Viejo, Jordi Arbiol, Tiankai Zhang, Feng Gao, Monica Lira‐Cantu   +12 more
wiley   +1 more source

The shifting perception on antioxidants: The case of vitamin E and β-carotene

Redox Biology, 2015
Antioxidants are vital for aerobic life, and for decades the expectations of antioxidants as health promoting agents were very high. However, relatively recent meta-analyses of clinical studies show that supplementation of antioxidants does not result in
Misha F. Vrolijk, Antoon Opperhuizen, Eugène H.J.M. Jansen, Roger W. Godschalk, Frederik J. Van Schooten, Aalt Bast, Guido R.M.M. Haenen   +6 more
doaj   +1 more source

Neuron‐Derived Vesicular circMagi1 Restrains Vascular Repair After Ischemic Stroke by Promoting TRIM65‐Mediated ANXA2 Degradation

Advanced Science, EarlyView.
After ischemic stroke, injured neurons transfer circMagi1 to endothelial cells through extracellular vesicles. Within endothelial cells, circMagi1 binds ANXA2 and enhances its engagement with TRIM65, promoting ANXA2 ubiquitination and proteasomal degradation to constrain angiogenic repair.
Youkun Bi, Qun Liu, Baohua Zou, Wenyuan Wang, Xinlong Qiao, Lin Gao, Chaoxu Miao, Ningning Huang, Shuqing Tang, Rui Guo, Changqing Zeng, Ce Jia, Yuanchao Xue, Xuejun Guo, Jianjun Chen, Huiwen Wang, Guangju Ji   +16 more
wiley   +1 more source

Motivational interviewing and urine cotinine feedback to stop passive smoke exposure in children predisposed to asthma: a randomised controlled trial

Scientific Reports, 2017
We tested the effectiveness of a program consisting of motivational interviewing (MI) and feedback of urine cotinine to stop passive smoking (PS) in children at risk for asthma. Fifty-eight families with children 0–13 years with a high risk of asthma and
Sasha G. Hutchinson, Gerard van Breukelen, Constant P. van Schayck, Brigitte Essers, S. Katharine Hammond, Jean W. M. Muris, Frans J. M. Feron, Edward Dompeling   +7 more
doaj   +1 more source

Non‐Covalent Reversibly Photoconvertible Fluorescent Tags for Wash‐Free Protein Labeling

Advanced Science, EarlyView.
FAST proteins combined with one or two fluorogens undergo reversible fluorescence switching or photoconversion through photoisomerization. At low fluorogen concentration and high light intensity, they act as negative or positive photoswitchers and photoconvertible tags, which are promising for discriminating FAST variants.
Mrinal Mandal, Yuriy Shpinov, Aliénor Lahlou, Fivos Pham, Lina El Hajji, Ian Coghill, Eve Laureau, Marie‐Aude Plamont, Franck Perez, Thomas Le Saux, Isabelle Aujard, Arnaud Gautier, Ludovic Jullien   +12 more
wiley   +1 more source

A Molecularly Imprinted Polymer-based Dye Displacement Assay for the Rapid Visual Detection of Amphetamine in Urine

Molecules, 2020
The rapid sensing of drug compounds has traditionally relied on antibodies, enzymes and electrochemical reactions. These technologies can frequently produce false positives/negatives and require specific conditions to operate.
Joseph W. Lowdon, Kasper Eersels, Rocio Arreguin-Campos, Manlio Caldara, Benjamin Heidt, Renato Rogosic, Kathia L. Jimenez-Monroy, Thomas J. Cleij, Hanne Diliën, Bart van Grinsven   +9 more
doaj   +1 more source

Structural Variants in the Human Genome Associated With Gut Microbiome and Blood Metabolic Traits With Potential Causal Links

Advanced Science, EarlyView.
Based on a multi‐omics cohort of 2002 individuals comprising high‐depth whole‐genome and metagenomic sequencing data, blood metabolites, and detailed questionnaires, we identified 138 859 high‐confidence SVs, uncovering 36 significant SV–microbiome associations and 48 SV–blood metabolite associations.
Qun Zhou, Keqing Wang, Junhong Chen, Haoyu Wang, Xinjiang Tan, Xuanlin Huang, Zhiyin Lin, Xun Xu, Xin Jin, Shaoqiao Zhang, Liang Xiao, Yuanqiang Zou, Tao Zhang, Xiaomin Liu   +13 more
wiley   +1 more source

Opinion 616

, 1961
(Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
openaire   +2 more sources