Results 21 to 30 of about 2,903,108 (215)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Памяти академика Вячеслава Всеволодовича Иванова (1929–2017)
Slavistica Vilnensis, 2018 [текст на русском]
Slavistica Vilnensis 2017 62
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FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
四川大学学报. 自然科学版, 2011 在四川大学CS30回旋加速器上通过核反应62Cu（p,2n）62Zn进行了62Zn-62Cu发生器母体核素62Zn的制备研究.实验选用高纯度的天然铜靶作为靶材料,研究了辐照铜靶的溶解与放射化学分离方法,并初步考察了62Zn-62Cu发生器的工艺参数.结果表明,采用26MeV的质子轰击天然铜,并用Dowex-1X8阴离子交换树脂对Zn与Cu等进行分离,可得到约3.7～11.1MBq/μA·h的62Zn.采用φ7×80 mm的玻璃柱作为62Zn-62Cu发生器吸附柱、200～400 mesh的Dowex1 ...
张华明 +7 more
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FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
CCPS 6(2), August/September 2020 [PDF]
Contemporary Chinese Political Economy and Strategic Relations: An International Journal, 2020 Contemporary Chinese Political Economy and Strategic Relations: An International Journal (CCPS), Vol. 6, No. 2, August/September 2020, pp. 409-817 (409 pp. + xii).
Emile Kok-Kheng Yeoh (ed.)
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