Results 31 to 40 of about 204,679 (250)

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source

Economical synthesis of silver nanoparticles using leaf extract of Acalypha hispida and its application in the detection of Mn(II) ions

Journal of Advanced Research, 2017
This study was focused on the synthesis of silver nanoparticles using Acalypha hispida leaf extract and the characterization of the particles using UV–Vis spectroscopy, XRD, FT-IR, and TEM.
R. Sithara, P. Selvakumar, C. Arun, S. Anandan, P. Sivashanmugam   +4 more
doaj   +1 more source

Spatial and Volumetric Characteristics of Glioblastoma: Associations With Clinical Presentation and Survival

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We aim to comprehensively analyze how regional tumor and edema characteristics are associated with clinical presentations and survival outcomes in a large cohort of glioblastoma patients. Methods Patients with IDH‐wildtype glioblastoma who received brain MRI from 2010 to 2023 were included.
Daniel J. Zhou, Marc Jaskir, Julian Gal, Yombe Fonkeu, Christos Davatzikos, MacLean P. Nasrallah, Jose Garcia, Rubo Xing, Stephen J. Bagley, Arati Desai, Richard E. Phillips, Steven Tobochnik, Colin A. Ellis, James J. Gugger, Nishant Sinha, Joel M. Stein, Kathryn A. Davis   +16 more
wiley   +1 more source

An End-To-End Secure Mobile Payment System Using Public Key Infrastructure System

Journal of Algorithms & Computational Technology, 2012
The exponential growth of wireless technologies and mobile devices, the mobile commerce becomes a significant for every one's life. Its popularity introduces a new channel for the research that is, M-Payment or Mobile Payment in terms of identifying new ...
S. Britto, R. Kumar, S. Albert Rabara
doaj   +1 more source

Econometric modelling for harvested area, production and productivity of natural rubber (Hevea brasiliensis)

The Indian Journal of Agricultural Sciences, 2020
The objective of present investigation was to study the trends in harvested area, production and productivity, and growth rates of natural rubber (Hevea brasiliensis) in Tamil Nadu from April 1991 to March 2016 by employing parametric models. The annual
SHYJU MATHEW, RAMASAMY MURUGESAN
doaj   +1 more source

Slip Localization Intensification Mediated by Grain Boundary Sliding in a Polycrystalline Nickel‐Based Superalloy

Advanced Engineering Materials, EarlyView.
The temperature dependence of fatigue behavior in nickel‐based superalloys is investigated through high‐resolution measurements of plastic localization. While increasing temperature reduces localization and enhances fatigue performance in René 88DT, Inconel 718 exhibits a sharp degradation at intermediate temperature due to intensified slip ...
M. Calvat, D. Anjaria, I. Woo, C. Bean, D. Texier, J. C. Stinville   +5 more
wiley   +1 more source

An overlapping Schwarz method for singularly perturbed fourth-order convection-diffusion type

Mathematical Modelling and Analysis, 2020
In this paper, we have constructed an iterative numerical method based on an overlapping Schwarz procedure with uniform mesh for singularly perturbed fourth-order of convection-diffusion type.
J. Christy Roja, Ayyadurai Tamilselvan
doaj   +1 more source

Creep‐Induced Microstructural Evolution in an A2‐B2 Superalloy

Advanced Engineering Materials, EarlyView.
A 27.3Ta‐27.3Mo‐27.3Ti‐8Cr‐10Al (at.%) refractory high‐entropy alloy with precipitation‐strengthened A2‐B2 microstructure was studied by creep tests at 1030°C, which demonstrate a transition in deformation mechanisms in the range of 100–150 MPa applied stress. This is associated with changes in dislocation–precipitate interactions. Relevant deformation
Liu Yang, Aparajita Pramanik, Sandipan Sen, Shubhashis Dixit, Marcel Muench, R. J. Vikram, Daniel Schliephake, Yolita M. Eggeler, Ankur Chauhan, Martin Heilmaier, Alexander Kauffmann   +10 more
wiley   +1 more source

Effect of cerium addition on corrosion behaviour of AZ61 + XCe alloy under salt spray test

Alexandria Engineering Journal, 2016
The corrosion behaviour of Mg–6Al–1Zn + XCe (where X = 0.5, 1.0, 1.5 and 2.0 wt% Ce) alloys, aged for 18 h at different temperatures of 180 °C, 200 °C, 220 °C and 240 °C, was studied in 3.5 wt% NaCl solution.
S. Manivannan, Sarathy Kannan Gopalakrishnan, S.P. Kumaresh Babu, Srinivasan Sundarrajan   +3 more
doaj   +1 more source