Results 271 to 280 of about 1,160,348 (369)

A model‐based analysis of the CYP2C9 genotype effects on fluconazole inhibition using flurbiprofen, ketoprofen and tolbutamide as probe drugs

British Journal of Pharmacology, EarlyView.
Background The activity of CYP2C9, an important drug metabolism enzyme, is subject to the impact of genetic polymorphism. The single nucleotide polymorphism *3 is significantly associated with the increased exposure of CYP2C9 substrates. In addition, metabolic enzyme inhibitors such as fluconazole may also increase the drug exposure of CYP2C9 ...
Shen Cheng, Darcy R. Flora, Mutaz M. Jaber, Allan E. Rettie, Richard C. Brundage, Timothy S. Tracy   +5 more
wiley   +1 more source

Src Reduces Neutrophil Extracellular Traps Generation and Resolves Acute Organ Damage. [PDF]

Adv Sci (Weinh)
Lu G, Han F, Wang Y, Yuan C, Zhu Q, Xia T, Chen L, Dong X, Ding Y, Xiao W, Zhang Y, Pan J, Xu H, Chen W, Tu B, Li W, Wang F, Gong W, Hu L.   +18 more
europepmc   +1 more source

I. Chmura-Rutkowska, E. Głowacka-Sobiech, I. Skórzyńska, „Niegodne historii”? O nieobecności i stereotypowych wizerunkach kobiet w świetle podręcznikowej narracji historycznej w gimnazjum, Wyd. Naukowe UAM, Poznań 2015, ISBN: 978-83-232-2867-7, ss. 621

, 2017
Jolanta Krucka
openalex   +2 more sources

Refining Tumor Mutational Burden as a Predictive Biomarker for Pembrolizumab: A Real‐World Analysis in Japanese Patients

Cancer Science, EarlyView.
In this study, we investigated the predictive value of tumor mutational burden (TMB) for assessing the efficacy of pembrolizumab in a Japanese cohort. We analyzed real‐world data from 63,952 patients registered in the C‐CAT database who underwent comprehensive genomic profiling, and evaluated the therapeutic efficacy of pembrolizumab in 1899 of these ...
Tomoyo Yasuda, Mio Yumura, Azusa Hamasaki, Tongyi Fei, Takashi Kubo, Hitoshi Ichikawa, Takashi Kohno, Kuniko Sunami   +7 more
wiley   +1 more source

Accrual of thromboembolic events and antiphospholipid syndrome in new-onset systemic lupus erythematosus: a population-based inception cohort study. [PDF]

RMD Open
Moe SR, Haukeland H, Brunborg C, Botea A, Damjanic N, Wivestad GÅ, Øvreås HK, Bøe TB, Orre A, Torhild G, Provan SA, Molberg Ø, Lerang K.   +12 more
europepmc   +1 more source

Correction to: ALKBH1 deficiency leads to loss of homeostasis in human diploid somatic cells. [PDF]

Protein Cell
europepmc   +1 more source

Correction: Evaluation of Prescription Practices for Antenatal Steroids in Pregnant. [PDF]

Matern Child Health J
Jano A, Madigan C, Ekeke P.
europepmc   +1 more source

Burning Down the House or Simply Rolling the Dice: A Comment on Section 621 of the Dodd-Frank Act and Recommendation for Its Implementation

, 2012
Joshua R. Rosenthal
openalex   +1 more source

ACTH Stimulation Testing Is Often Unnecessary After Appropriate Patient Preparation Prior to Screening Cortisol Measurement

Clinical Endocrinology, EarlyView.
ABSTRACT Context Screening morning serum cortisol is used to select patients for ACTH stimulation testing to diagnose adrenal insufficiency (AI) but may be affected by pre‐analytical factors. Careful consideration to discontinue confounding medications beforehand may preclude the need for subsequent stimulation testing.
Christopher J. Symonds, Alexander A. Leung, Gregory A. Kline   +2 more
wiley   +1 more source

Correction: Bosica, G.; Abdilla, R. Novel Biopolymer-Based Catalyst for the Multicomponent Synthesis of <i>N</i>-aryl-4-aryl-Substituted Dihydropyridines Derived from Simple and Complex Anilines. <i>Molecules</i> 2024, <i>29</i>, 1884. [PDF]

Molecules
Bosica G, Abdilla R.
europepmc   +1 more source