Results 11 to 20 of about 1,059,062 (379)

Extracellular vesicle-mediated regulation of imatinib resistance in chronic myeloid leukemia via the miR-629-5p/SENP2/PI3K/AKT/mTOR axis

Hematology
Background Imatinib (IM) is the primary treatment for patients with chronic-phase CML (CML-CP). However, an increasing number of CML-CP patients have developed resistance to IM.
Yaqin Jiang, Shishan Xiao, Shengwen Huang, Xuemei Zhao, Siruiyun Ding, Qianqian Huang, Wei Xiao, Zhe Li, Hongqian Zhu   +8 more
doaj   +2 more sources

MiR-629-5p Promotes Prostate Cancer Development and Metastasis by Targeting AKAP13

Frontiers in Oncology, 2021
Prostate cancer (PCa) has become the most frequently occurring cancer among western men according to the latest report, and patients’ prognosis is often poor in the event of tumor progression, therefore, many researches are devoted to exploring the ...
Yangzhou Liu, Shankun Zhao, Jiamin Wang, Zhiguo Zhu, Lianmin Luo, Qian Xiang, Mingda Zhou, Yuxiang Ma, Zuomin Wang, Zhigang Zhao   +9 more
doaj   +2 more sources

Circular RNA hsa_circ_0002360 Promotes Proliferation and Invasion and Inhibits Oxidative Stress in Gastric Cancer by Sponging miR-629-3p and Regulating the PDLIM4 Expression

Oxidative Medicine and Cellular Longevity, 2022
Many studies have found that circRNA hsa_0002360 (circ0002360) plays an important role in cancer onset and progression. However, its role in gastric cancer (GC) remains uncertain.
Zhengyuan Yu, Jing Lan, Wei Li, Li Jin, Fengxia Qi, Chen Yu, Hao Zhu   +6 more
semanticscholar   +1 more source

Upregulation of Serum miR-629 Predicts Poor Prognosis for Non-Small-Cell Lung Cancer

Disease Markers, 2021
Non-small-cell lung cancer (NSCLC) is one of the most common types of cancer worldwide. Accumulating evidence has suggested that aberrant expression of microRNAs (miRNAs) is involved in the carcinogenesis and progression of NSCLC.
Fayong Liu, Tian-shui Li, Ping Hu, L. Dai   +3 more
semanticscholar   +1 more source

Pembrolizumab Monotherapy for Recurrent or Metastatic Cutaneous Squamous Cell Carcinoma: A Single-Arm Phase II Trial (KEYNOTE-629)

Journal of Clinical Oncology, 2020
PURPOSE Treatment options are limited for patients with recurrent and/or metastatic (R/M) cutaneous squamous cell carcinoma (cSCC); mortality rates exceed 70% in patients with distant metastases.
J. Grob, R. Gonzalez, N. Basset-Seguin, O. Vornicova, J. Schachter, A. Joshi, N. Meyer, F. Grange, J. Piulats, J. Bauman, Pingye Zhang, B. Gumuscu, R. Swaby, B. Hughes   +13 more
semanticscholar   +1 more source

Health-Related Quality of Life of Patients with Recurrent or Metastatic Cutaneous Squamous Cell Carcinoma Treated with Pembrolizumab in KEYNOTE-629

Dermatologic Therapy, 2021
Pembrolizumab provided durable responses and acceptable safety in recurrent or metastatic (R/M) cutaneous squamous cell carcinoma (cSCC) in the KEYNOTE-629 study.
B. Hughes, R. G. Mendoza, N. Basset-Seguin, O. Vornicova, J. Schachter, A. Joshi, N. Meyer, F. Grange, J. Piulats, J. Bauman, D. Chirovsky, Pingye Zhang, B. Gumuscu, R. Swaby, J. Grob   +14 more
semanticscholar   +1 more source

Overexpression of Long Non-Coding RNA MIR22HG Represses Proliferation and Enhances Apoptosis via miR-629-5p/TET3 Axis in Osteosarcoma Cells

Journal of Microbiology and Biotechnology, 2021
In this study, we evaluated the mechanism of long non-coding RNA MIR22 host gene (LncRNA MIR22HG) in osteosarcoma cells. Forty-eight paired osteosarcoma and adjacent tissues samples were collected and the bioinformatic analyses were performed.
Haoliang Zhao, Ming Zhang, Xuejing Yang, D. Song   +3 more
semanticscholar   +1 more source

Circular RNA circNRIP1 promotes migration and invasion in cervical cancer by sponging miR-629-3p and regulating the PTP4A1/ERK1/2 pathway

Cell Death and Disease, 2020
Emerging evidence indicates that circRNAs play essential roles in tumorigenesis and development. However, the role of circRNAs in cervical cancer (CC) remains unclear.
Xinhui Li, Ningye Ma, Yao Zhang, Heng Wei, Huijie Zhang, Xiaoao Pang, Xia Li, Dan-Dan Wu, Dian Wang, Zhuo Yang, Shulan Zhang   +10 more
semanticscholar   +1 more source

The Level of Conus Medullaris in 629 Healthy Japanese Individuals

Journal of Clinical Medicine, 2021
The conus medullaris typically terminates at the L1 level; however, variations in its level and the factors associated with the conus medullaris level are unclear.
H. Nakashima, Keigo Ito, Yoshito Katayama, Mikito Tsushima, K. Ando, Kazuyoshi Kobayashi, M. Machino, S. Ito, Hiroyuki Koshimizu, Naoki Segi, H. Tomita, S. Imagama   +11 more
semanticscholar   +1 more source

LncRNA MAGI2-AS3 acts as a tumor suppressor that attenuates non-small cell lung cancer progression by targeting the miR-629-5p/TXNIP axis

Annals of Translational Medicine, 2021
Background Lung cancer is a malignant tumor that seriously threatens the health of human beings. Long non-coding RNAs (lncRNAs) are thought to play important roles in the pathophysiology of lung cancer.
Jun Gong, Lei Ma, C. Peng, Jianhua Liu
semanticscholar   +1 more source