Results 1 to 10 of about 36 (33)
On Sequential Treatment Allocations in Clinical Trials [PDF]
This dissertation treats baseline-dependent sequential designs of two-treatment parallel-group clinical trials. The treatment assignments are chosen in order to minimize the variance, in a linear model, of the treatment effect.
Burman, Carl-Fredrik,
core +4 more sources
Adaptive numerical designs for the calibration of computer codes [PDF]
AMS subject classifications. 62K99, 62L05, 60G15Making good predictions of a physical system using a computer code requires the inputs to be carefully specified. Some of these inputs, called control variables, reproduce physical conditions, whereas other
Damblin, Guillaume +11 more
core +1 more source
Asymptotic optimality of sequential designs for estimation
This paper is concerned with the problem of allocating a fixed number of trials between K independent populations from the exponential family, in order to estimate a linear combination of the means with squared error loss. Introducing independent conjugate priors, a batch sequential procedure is proposed and compared with the optimal.
Kamel Rekab
wiley +1 more source
The problem of designing an experiment to estimate the product of the means of two normal populations is considered. A Bayesian approach is adopted in which the product of the means is estimated by its posterior mean. A fully sequential design is proposed and shown to be asymptotically optimal.
Kamel Rekab
wiley +1 more source
Asymptotic optimality of experimental designs in estimating a product of means
In nonlinear estimation problems with linear models, one difficulty in obtaining optimal designs is their dependence on the true value of the unknown parameters. A Bayesian approach is adopted with the assumption the means are independent apriori and have conjuguate prior distributions.
Kamel Rekab
wiley +1 more source
Empirical likelihood ratio tests with power one. [PDF]
Vexler A, Zou L.
europepmc +1 more source
Group sequential crossover trial designs with strong control of the familywise error rate. [PDF]
Grayling MJ, Wason JMS, Mander AP.
europepmc +1 more source
Asymptotic properties of maximum likelihood estimators with sample size recalculation. [PDF]
Tarima S, Flournoy N.
europepmc +1 more source
Pattern-mixture-type Estimation and Testing of Neuroblastoma Treatment Regimes. [PDF]
Tang X, Wahed AS.
europepmc +1 more source

