Results 1 to 10 of about 59 (55)
Derivation of a health-based guidance value for Δ<sup>8</sup>-tetrahydrocannabinol (Δ<sup>8</sup>-THC) and its occurrence in food. [PDF]
EFSA JAbstract
The European Food Safety Authority (EFSA) was asked to deliver a scientific opinion on the derivation of a health‐based guidance value (HBGV) for Δ8‐tetrahydrocannabinol (Δ8‐THC) in food with an assessment of the occurrence of Δ8‐THC and the co‐occurrence with Δ9‐THC in hemp and hemp‐derived products.EFSA Panel on Contaminants in the Food Chain (CONTAM), Knutsen HK, Åkesson A, Bampidis V, Bignami M, Chipman JK, Degen G, Hernández-Jerez A, Hofer T, Hogstrand C, Landi S, Leblanc JC, Machera K, Ntzani E, Oswald IP, Rychen G, Sand S, Vejdovszky K, Viviani B, Dusemund B, Nebbia C, Weigel S, Cascio C, Christodoulidou A, Abrahantes JC, Dujardin B, Gissi A, Asensio LA, Gkimprixi E, Tauriainen T, Bodin L. +30 moreeuropepmc +2 more sourcesProspective evaluation of the tolerability and efficacy of niraparib dosing based on baseline body weight and platelet count: Results from the PRIMA/ENGOT‐OV26/GOG‐3012 trial
Cancer, Volume 129, Issue 12, Page 1846-1855, 15 June 2023., 2023 Abstract Background
The PRIMA/ENGOT‐OV26/GOG‐3012 (NCT02655016) trial was amended to prospectively evaluate the safety and efficacy of an individualized starting dose (ISD) regimen of niraparib for first‐line maintenance therapy in patients with newly diagnosed advanced ovarian cancer.Mansoor R. Mirza, Antonio González‐Martín, Whitney S. Graybill, David M. O’Malley, Lydia Gaba, Oi Wah Stephanie Yap, Eva M. Guerra, Peter G. Rose, Jean‐François Baurain, Sharad A. Ghamande, Hannelore Denys, Emily Prendergast, Carmela Pisano, Philippe Follana, Klaus Baumann, Paula M. Calvert, Jacob Korach, Yong Li, Izabela A. Malinowska, Divya Gupta, Bradley J. Monk +20 morewiley +1 more sourceThe clinical features, management and outcomes of lymphoma in pregnancy: A multicentre study by the Australasian Lymphoma Alliance
British Journal of Haematology, Volume 201, Issue 5, Page 887-896, June 2023., 2023 Summary
Lymphoma in pregnancy (LIP) presents unique clinical, social and ethical challenges; however, the evidence regarding this clinical scenario is limited. We conducted a multicentre retrospective observational study reporting on the features, management, and outcomes of LIP in patients diagnosed between January 2009 and December 2020 at 16 sites ...Pietro R. Di Ciaccio, Georgia Mills, Michael J. Shipton, Belinda Campbell, Gareth Gregory, Jenna Langfield, Matthew Greenwood, Sean McKeague, Mohammad Shanavas, Renee Eslick, Giselle Kidson‐Gerber, Portia Smallbone, Catherine Tang, Kirk Morris, Ian Bilmon, Costas K. Yannakou, Xavier Badoux, Leanne Berkahn, Sergio Farina, Kylie D. Mason, Penelope Motum, Kathryn Goss, Nada Hamad +22 morewiley +1 more sourceMatching‐adjusted indirect comparison of isatuximab plus carfilzomib and dexamethasone with daratumumab plus lenalidomide and dexamethasone in relapsed multiple myeloma
Cancer Medicine, Volume 12, Issue 7, Page 8005-8017, April 2023., 2023 Matching‐adjusted indirect comparison results for Isa‐Kd vs. Dara‐Rd: Kaplan‐Meier curves of progression‐free survival before matching and after inclusion criteria selection (A) and after matching (B); Kaplan‐Meier curves of overall survival before matching and after inclusion criteria selection (C) and after matching (D). CI, confidence interval; Dara‐Joshua Richter, Peggy L. Lin, Viviana Garcia‐Horton, Patricia Guyot, Erin Singh, Zheng‐Yi Zhou, Mark Sievert, Riley Taiji +7 morewiley +1 more sourcePrognostic impact of MYD88 and CXCR4 mutations assessed by droplet digital polymerase chain reaction in IgM monoclonal gammopathy of undetermined significance and smouldering Waldenström macroglobulinaemia
British Journal of Haematology, Volume 200, Issue 2, Page 187-196, January 2023., 2023 Summary
Waldenström macroglobulinaemia (WM) is characterized by recurrent somatic mutations in MYD88 and CXCR4 genes. However, limitations arise when analysing these mutations in IgM monoclonal gammopathy of undetermined significance (MGUS) or smouldering WM (SWM) given the lower tumour load.David F. Moreno, Mónica López‐Guerra, Sara Paz, Aina Oliver‐Caldés, Mari‐Pau Mena, Juan G. Correa, Anthony M. Battram, Miguel Osuna, Alfredo Rivas‐Delgado, Luis Gerardo Rodríguez‐Lobato, Oriol Cardús, Natalia Tovar, María Teresa Cibeira, Raquel Jiménez‐Segura, Joan Bladé, Laura Rosiñol, Dolors Colomer, Carlos Fernández de Larrea +17 morewiley +1 more sourceA Phase 2a Study Evaluating the Safety and Pharmacokinetics (PK) of Luspatercept in Pediatric Patients with Transfusion-Dependent ss-Thalassemia (TDT)
, 2021 63rd Annual Meeting and Exposition of the American-Society-of-Hematology (ASH) -- DEC 11-14, 2021 -- Atlanta, GA[No Abstract Available]Amer Soc ...Aydinok, Yesim, Coates, Thomas D., Musallam, Khaled M., Patturajan, Meera, Viprakasit, Vip, Buerki, Julie Vienne, Holot, Natalia +6 morecore +1 more sourceTurning the tide? Economic reforms and union revival in India
Industrial Relations Journal, Volume 52, Issue 4, Page 364-385, July 2021., 2021 Abstract
Despite nearly three decades of ostensibly pro‐employer economic reforms in India, trade union membership and density in India appear to have risen. Although similar trends have been reported and investigated in other emerging economies such as China and South Africa, the union revival thesis in India is yet to be fully explored.Vidu Badigannavar, John Kelly, Manik Kumar +2 morewiley +1 more sourceIdarucizumab for Reversal of Dabigatran: Multicenter Real-World Experience
, 2021 20.500.12530 ...Fernandez, Begona, Meijon, Mar, Rosado Sierra, Belen, Gutierrez, Isabel, Diez-Martin, Jose L., Blaco Banares, Maria Jesus, Llamas Sillero, Maria Pilar, Revilla Calvo, Nuria, Asenjo Correa, Susana, Rodriguez-Gonzalez, Ramon, Perez-Rus, Gloria, Pascual Izquierdo, Cristina, Sola Aparicio, Maria Elena, Barzallo Burbano, Paola Alejandra +13 morecore +1 more sourceEfficacy of Ibrutinib, Rituximab and Mini-CHOP in Very Elderly Patients with Newly Diagnosed Diffuse Large B Cell Lymphoma: Primary Analysis of the Australasian Leukaemia & Lymphoma Group NHL29 Study
, 2021 Introduction: R-mini-CHOP is an established standard of care in elderly patients with DLBCL, with a 2yr OS of 59% and PFS of 47% (Peyrade et al, Lancet Oncol 2011). The addition of ibrutinib to full dose R-CHOP in younger pts with DLBCL has efficacy, but Johnston, Amanda, Lee, Hui-Peng, Cheah, Chan-Yoon, Sia, Hanlon, Brown, Christina, Hawkes, Eliza, Curnow, Jennifer, Pati, Nalini, Murphy, Nicholas E, Filshie, Robin J, Verner, Emma, Cochrane, Tara, Lee, Kenneth, Enjeti, Anoop Kumar, et al., Purtill, Duncan +15 morecore +1 more source