Results 101 to 110 of about 1,066 (137)
Some of the next articles are maybe not open access.
Cancer Research, 2022
Background: KRASG12C mutation is an oncogenic driver that occurs in approximately 15% of non-small cell lung cancer (NSCLC), 3% of colorectal cancer (CRC), and ~1% of several other solid tumors.
Timothy Price +18 more
semanticscholar +1 more source
Background: KRASG12C mutation is an oncogenic driver that occurs in approximately 15% of non-small cell lung cancer (NSCLC), 3% of colorectal cancer (CRC), and ~1% of several other solid tumors.
Timothy Price +18 more
semanticscholar +1 more source
Cancer Research, 2022
Cancer-induced cachexia is commonly observed in pancreatic cancer. The syndrome induces significant weight loss and leads to morbidity, intolerance to chemotherapy, and mortality.
B. Krishnamachary +11 more
semanticscholar +1 more source
Cancer-induced cachexia is commonly observed in pancreatic cancer. The syndrome induces significant weight loss and leads to morbidity, intolerance to chemotherapy, and mortality.
B. Krishnamachary +11 more
semanticscholar +1 more source
Cancer Research, 2022
Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal malignancy with a proclivity for early metastasis. Resection remains the only chance for long term survival though most patients die from metastatic recurrence. While most patients recur within
A. Casabianca +3 more
semanticscholar +1 more source
Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal malignancy with a proclivity for early metastasis. Resection remains the only chance for long term survival though most patients die from metastatic recurrence. While most patients recur within
A. Casabianca +3 more
semanticscholar +1 more source
Cancer Research, 2022
Background: MAPK pathway dysregulation is a characteristic molecular abnormality of melanoma. NRAS mutations in melanoma lead to constitutive MAPK activation and subsequent MEK and ERK activation.
F. de Braud +26 more
semanticscholar +1 more source
Background: MAPK pathway dysregulation is a characteristic molecular abnormality of melanoma. NRAS mutations in melanoma lead to constitutive MAPK activation and subsequent MEK and ERK activation.
F. de Braud +26 more
semanticscholar +1 more source
Abstract 3154: Assessing hematopoietic stem cell fitness within a nanobioreactor in microgravity
Cancer Research, 2022Microgravity coupled with increased radiation exposure aboard the ISS provides a unique environment to simulate and study response to injury, inflammatory signaling, aging, and (pre-)malignant transformation of normal human hematopoietic stem cells ...
Luisa Ladel +4 more
semanticscholar +1 more source
Cancer Research, 2022
Background: Genomic profiling with tissue sequencing is still considered as the gold standard despite several limitations including screening failures due to limited tissue availability, and inability to capture intratumor spatial and temporal ...
A. Bayle +19 more
semanticscholar +1 more source
Background: Genomic profiling with tissue sequencing is still considered as the gold standard despite several limitations including screening failures due to limited tissue availability, and inability to capture intratumor spatial and temporal ...
A. Bayle +19 more
semanticscholar +1 more source
Fully Remote Software Development as a New Standard in the IT Industry: European Study 2022—2023
PROGRAMMNAYA INGENERIA, 2023The pandemic and the emergence of the COVID-economy continue to have a significant impact on the organization of labor in the industries of the "new economy", of which the information technology industry is a prominent representative.
D. Pashchenko
semanticscholar +1 more source
Journal of Clinical Oncology, 2023
3001 Background: BL-B01D1 is a first-in-class novel ADC consisting of an EGFRxHER3 bispecific antibody linked to a novel TOP-I inhibitor payload via a cleavable linker. We now present safety/efficacy results from a FIH phase I study of BL-B01D1. Methods:
Li Zhang +18 more
semanticscholar +1 more source
3001 Background: BL-B01D1 is a first-in-class novel ADC consisting of an EGFRxHER3 bispecific antibody linked to a novel TOP-I inhibitor payload via a cleavable linker. We now present safety/efficacy results from a FIH phase I study of BL-B01D1. Methods:
Li Zhang +18 more
semanticscholar +1 more source
Comparison of Maternal and Perinatal Outcome Between 4 cm vs 6 cm Cervical Dilatation at Amniotomy
Pakistan Armed Forces Medical JournalObjective: To compare maternal and perinatal outcome between 4 cm vs 6 cm cervical dilatation at Amniotomy among women undergoing induction of labor at our unit. Study Design: Comparative cross-sectional study.
Seema Tariq, T. Yazdani
semanticscholar +1 more source
Clinical Cancer Research
Background: The implementation of germline genetic testing is complex due to emerging therapeutic indications such as adjuvant Olaparib for BRCA-mutated breast cancer (BC).
Adela Rodriguez Hernandez Barbara Adamo +17 more
semanticscholar +1 more source
Background: The implementation of germline genetic testing is complex due to emerging therapeutic indications such as adjuvant Olaparib for BRCA-mutated breast cancer (BC).
Adela Rodriguez Hernandez Barbara Adamo +17 more
semanticscholar +1 more source