Results 111 to 120 of about 941,914 (307)

Prediction of the individual risk for the development of brain metastases in patients with non‐oncogene‐addicted non‐small cell lung cancer: Real‐world data from the German prospective CRISP registry (AIO‐TRK‐0315)

International Journal of Cancer, EarlyView.
What's New? Estimating the risk of developing brain metastases may enable earlier diagnosis and treatment, potentially reducing morbidity and mortality. Using the prospective CRISP lung cancer registry, the authors developed and validated a point‐based classifier for the risk of developing first brain metastases in patients with advanced or metastatic ...
Fabian Acker, Katharina Wenger, Martin Reck, Cornelius F. Waller, Petra Hoffknecht, Andre Bethge, Arnd Nusch, Marcel Reiser, Christiane Bernhardt, Michael Bendel, Carolin Lennartz, Annette Fleitz, Martina Jänicke, Paula Ludwig, Annika Groth, Frank Griesinger, Michael Thomas, Wilfried E. E. Eberhardt, Martin Sebastian, for the CRISP Registry Group   +19 more
wiley   +1 more source

High-frequency stock price prediction via deep learning

Machine Learning with Applications
We performed a comparative analysis of deep learning methods for high-frequency stock price prediction. Instead of directly analyzing one-dimensional stock price time series data, this study employs the Gramian Angular Summation Field method (Wang and ...
Jianlong Bao, Takayuki Morimoto
doaj   +1 more source

Development of New Chemotherapeutics for Head & Neck Squamous Cell Carcinoma (HNSCC) [PDF]

, 2013
The signal transducers and activators of transcription STAT3 and STAT1 share common structure and targets, but they play opposing roles in tumorigenesis.
Wang, Zhuzhu
core   +1 more source

A Hybrid Model for Forecasting Realized Volatility Based on Heterogeneous Autoregressive Model and Support Vector Regression

Risks
In this study, we proposed two types of hybrid models based on the heterogeneous autoregressive (HAR) model and support vector regression (SVR) model to forecast realized volatility (RV).
Yue Zhuo, Takayuki Morimoto
doaj   +1 more source

Paternal Exposure to the Neonicotinoid Pesticide Clothianidin Alters Sperm MicroRNA Profiles in Mice and Intergenerationally Reduces Locomotor Activity in Male Offspring

Journal of Applied Toxicology, EarlyView.
ABSTRACT Accumulating evidence suggests that paternal environmental factors have epigenetic effects on sperm and influence offspring. Neonicotinoid pesticides (NNs), which are widely used around the world, are known to affect offspring phenotypes through maternal exposure in mice, but the effect of the paternal exposure remains unknown.
Makiko Ito, Tetsushi Hirano, Sarika Nunobiki, Ayano Yoshimoto, Yukako Hara, Yuya Ishida, Sakura Yonoichi, Youhei Mantani, Toshifumi Yokoyama, Yoshiaki Tabuchi, Yoshinori Ikenaka, Nobuhiko Hoshi   +11 more
wiley   +1 more source

New Hydrazone Derivatives Featuring Isatin and Piperazine Moieties: Synthesis, Cytotoxicity Evaluation, and Molecular Modeling Studies

Journal of Applied Toxicology, EarlyView.
ABSTRACT In this study, ten novel compounds (IPH1–IPH10) were designed by integrating three pharmacophores (isatin, piperazine, and hydrazone) commonly found in the molecular structures of anticancer agents. The target molecules were obtained by the reaction of in‐house prepared 4‐(4‐(pyridin/pyrimidin‐2‐yl)piperazin‐1‐yl)benzohydrazide with various ...
Semiha Köprü, Münevver Baran, Miyase Gözde Gündüz, Şengül Dilem Doğan   +3 more
wiley   +1 more source

Longitudinal associations between play experiences and trajectories of preschoolers' mental health from April–July, 2020

JCPP Advances, EarlyView.
Based on data collected monthly from April to July 2020, we found that time spent playing outside and with other children were associated with lower internalising problems across time in preschool‐aged children, whereas more time spent playing alone was associated with more severe internalising problems.
Helen F. Dodd, Ella Patterson, Simona Skripkauskaite, Peter J. Lawrence   +3 more
wiley   +1 more source

Positive developmental cascades: Strength development reduces support needs in children

JCPP Advances, EarlyView.
Abstract Background Strength development in children across a range of psychiatric diagnoses may reduce needs for mental health, social, and functioning support over time. A strength‐based adjunct to child and adolescent mental health may foster the developmental context most helpful for achieving desired outcomes with positive developmental cascading ...
Melody R. Altschuler, Xiaoran Tong, Punit Shah, Edelyn Verona, Julianne M. Bowling, Robert F. Krueger, Roman Kotov, Jordan H. McAllister, Michaela Voit, Sachina Paudel, Scott C. Leon, Shashwat Kala, John S. Lyons   +12 more
wiley   +1 more source

Effects of genotype and environment on the physiochemical properties of Canadian oat varieties

Journal of the Science of Food and Agriculture, Volume 105, Issue 5, Page 3111-3121, 30 March 2025.
Abstract BACKGROUND The relationship between oat grain composition and physical attributes as influenced by oat genotype and Canadian growing environments was investigated. Thirty Canadian oat (Avena sativa L.) genotypes, grown in three Canadian growing locations (Brandon, Manitoba; Portage la Prairie, Manitoba; and Lacombe, Alberta) over 2 consecutive
Vanessa Alexander, Kirby T. Nilsen, Sijo Joseph, Trust Beta, Lovemore Nkhata Malunga   +4 more
wiley   +1 more source

Geochemical Characteristics of the Hida Granitoids in the Unazuki and Katakaigawa Areas, Central Japan

Geosciences
The Hida Belt in central Japan is a key geological unit for understanding the crustal growth of the Eurasian continent in the Mesozoic. However, while previous studies have focused primarily on geochronology, the geochemical characteristics of its rocks ...
Kazuki Oishi, Rui Kuwahara, Kazuya Shimooka, Motohiro Tsuboi   +3 more
doaj   +1 more source