Safety pharmacology of acute mescaline administration in healthy participants
Aims Psychedelics, including mescaline, may serve as novel treatments for depression and anxiety. However, data is scarce on the safety of mescaline. Methods The present pooled analysis included two double‐blind, randomized, placebo‐controlled studies with a total of 48 participants and 96 mescaline administrations. Single oral‐dose administrations (n =
Aaron Klaiber +4 more
wiley +1 more source
RNA-binding protein transcripts reflect composition of target mRNAs. [PDF]
Kapral TH, Žagrović B.
europepmc +1 more source
Disciplining the “Queen of the World”? Responsible Innovation as a Way of Life
ABSTRACT This paper offers a critical reflection on the concept of responsible innovation as defined during the last decades. We argue that the emphasis on innovation as a process risks neglecting the very goals of innovation, namely societal desirability and acceptability. Thus, we suggest reconsidering the role of imagination, the “Queen of the world”
Xavier Pavie +2 more
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Molecular Composition and Ligand Binding Characteristics of Native Ionotropic GABA Receptors in Rice Stem Borer, <i>Chilo suppressalis</i>. [PDF]
Zhan E +5 more
europepmc +1 more source
Abstract Objectives Theoretical models implicate social anxiety and worry as potential drivers of paranoia; however, it is unknown which aspect of anxiety relates more strongly to paranoia, whether these relationships differ in clinical versus non‐clinical populations and how these variables relate to one another over time.
Brandee Feola +6 more
wiley +1 more source
Retraction Note: Synergistic effects of combinatorial chitosan and polyphenol biomolecules on enhanced antibacterial activity of biofunctionalized silver nanoparticles. [PDF]
Rezazadeh NH, Buazar F, Matroodi S.
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Abstract Background Exams are a common source of emotions in adolescence, requiring regulation for performance and well‐being. Psychological flexibility (PF), the ability to stay open to difficult thoughts and feelings while pursuing meaningful goals, and psychological inflexibility (PI), involving avoidance and self‐criticism, represent adaptive and ...
Maryam Zarra‐Nezhad +4 more
wiley +1 more source
Summary Preclinical and clinical studies suggest that selective serotonin reuptake inhibitors (SSRIs) can stimulate haematopoiesis by promoting proliferation and mobilization of haematopoietic stem and progenitor cells, but whether SSRI use influences myeloid malignancy risk remains unclear.
Katrine Mose +5 more
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The Roles of Alix and VPS4A in Autophagy and Endosomal Pathways and Their Relation to HBV Replication. [PDF]
Li J +5 more
europepmc +1 more source
Task‐specific associations between holistic processing and individual differences in face memory
Abstract Whether individual differences in face identification can be predicted by holistic processing, and whether both share a common underlying mechanism, remain open questions. Past studies exploring this association have produced mixed findings, but they have typically examined only a subset of holistic processing measures, focused largely on ...
Bryan Qi Zheng Leong +2 more
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