Results 191 to 200 of about 214,462 (292)

Phosphorylated STYK1 Promotes Gemcitabine Resistance via Autophagy‐Mediated Cancer Stemness in Pancreatic Cancer

Advanced Science, EarlyView.
Gemcitabine resistance remains a major challenge in pancreatic ductal adenocarcinoma. This study identifies STYK1 as a key mediator of chemoresistance through autophagy‐dependent maintenance of cancer stemness. Gemcitabine‐activated AMPK phosphorylates STYK1 at Ser91 and Ser304, enhancing autophagy and stemness.
Xueying Dong, Shi Li, Chensong Huang, Xuehong Qian, Jieyu Guo, Yahao Guo, Guifang Wu, Qi Zhang, Hongfei Tan, Yu Han, Rui Zhang, Hao Lyu, Shuai Xiao, Dong Guo, Chaojun Yan, Wenying Qin, Changchun Li, Xing‐Zhen Chen, Ying Zhao, Cefan Zhou, Jingfeng Tang   +20 more
wiley   +1 more source

定量检测痕量罗丹明6G的方法

 一种利用拉曼光谱仪定量检测痕量罗丹明6G的方法,包括以下步骤：采用交流电化学沉积法制备多个银纳米线阵列：以硝酸银/硼酸混合水溶液为电解液向AAO模板的孔洞中限域沉积银纳米线,形成银纳米线阵列；制备银纳米颗粒,并分别与不同浓度的罗丹明6G溶液混合,分别滴在制备好的银纳米线阵列上,形成SERS增强“三明治”体系；待“三明治”体系自然干燥后,在拉曼光谱仪上对其进行拉曼光谱测试,得到不同浓度罗丹明6G溶液的SERS谱 ...
张君梦, 王占国, 曲胜春, 张利胜   +3 more
core  

Advanced Handover Decision with Mobility Awareness for 5G/6G Mobile Networks in Ultra-Dense and Smart Cities Area. [PDF]

Sensors (Basel)
Loutfi SI, Shayea I, Tureli U, Tashan W, Aldasheva L, Amirova A, Yedilkhan D, Amanzholova S.   +7 more
europepmc   +1 more source

TRAIP Mediates Alcohol‐Induced Liver Injury through Regulating β‐catenin Ubiquitin Degradation via Direct Interaction

Advanced Science, EarlyView.
This study reveals that NF‐κB1‐driven TRAIP upregulation in ALD correlates with disease severity. Mechanistically, TRAIP directly binds β‐catenin via its CC domain and promotes its K48‐linked ubiquitination and degradation, which is independent of the GSK3β/β‐TrCP pathway.
Zhan Wu, Mingjiang Liu, Lijuan Liao, Zhaohong Mo, Wenli Xu, Linfeng Mao, Yubing Chen, Qiuli Xie, Ming Yao, Shilian Chen, Stephen Tomlinson, Sebastian Mueller, Songqing He, Guandou Yuan   +13 more
wiley   +1 more source

EEG and ECG Wearable Biosensor-Based Affective State Analysis Using Deep Learning over 6G IoT Healthcare Networks. [PDF]

Biosensors (Basel)
Bıçakcı Yeşilkaya HS, Özbaltan M, Özbaltan N, Şeker C, Yeşilkaya B, Yalçınkaya B.   +5 more
europepmc   +1 more source

PREDICT-6G: SNS JU 6G Architecture WG

This presentation about PREDICT-6G architecture was delivered by José Luis Cárcel (ATOS/EVIDEN), PREDICT-6G partner, in the SNS JU 6G Architecture WG Meeting on the 1 of March 2024. 
openaire   +2 more sources

Disrupted TFEB/GDNF–cAMP/ATP Coupling Underlies Astrocytic Dysfunction and Depression in LRRK2 G2019S Parkinson's Mice

Advanced Science, EarlyView.
ABSTRACT The LRRK2 G2019S mutation, a Parkinson's disease–linked variant, has been associated with depression‐like phenotypes, but mechanisms remain unclear. We chart age‐dependent behavioral changes and astrocyte reactivity in G2019S mice and define a pathway connecting LRRK2 to TFEB/GDNF signaling, cellular energetics, and inflammation.
Longping Yao, Maryam Hatami, Sumeyye Koc, Qing Jiang, Thomas Skutella, Yuanfeng Zhang   +5 more
wiley   +1 more source

Correction: Characterization of an AGAMOUS-like MADS Box Protein, a Probable Constituent of Flowering and Fruit Ripening Regulatory System in Banana. [PDF]

PLoS One
Choudhury SR, Roy S, Nag A, Singh SK, Sengupta DN.   +4 more
europepmc   +1 more source

Pre‐Regenerative Endothelial Cells Empowered by Antler Blood Exosomes Orchestrate Peripheral Nerve Repair

Advanced Science, EarlyView.
The pre‐regenerative vascular niche (PVN) is essential for nerve repair, yet its endothelial blueprint remains unclear. We identified angiogenic ECs (AECs) as the dominant pre‐regenerative subset and found that antler blood–derived exosomes (AB‐EXO) promote repair via IMP3.
Jinsheng Huang, Qiang Chen, Aihua Jin, Xiaoqi Yang, Hui Zhou, Weiquan Gong, Jin Cheng, Jun Dai, Minjin Wang, Meihua Piao, Yuanyi Wang, Nan Zhou   +11 more
wiley   +1 more source

New 6G solutions for mobile network coverage

openDagli anni Ottanta fino al giorno d’oggi le reti mobili hanno subito diverse innovazioni per gestire il crescente bisogno di connettività. Le prime generazioni erano create per soddisfare bisogni come invio di SMS o piccole ricerche sul web.
SCALCO, RICCARDO
core