Results 1 to 10 of about 1,024,674 (335)

Differential expression of CCR8 in tumors versus normal tissue allows specific depletion of tumor-infiltrating T regulatory cells by GS-1811, a novel Fc-optimized anti-CCR8 antibody

OncoImmunology, 2022
The presence of T regulatory (Treg) cells in the tumor microenvironment is associated with poor prognosis and resistance to therapies aimed at reactivating anti-tumor immune responses.
Jessica D. Weaver, Edward C. Stack, Joshua A. Buggé, Changyun Hu, Lara McGrath, Amy Mueller, Masie Wong, Boris Klebanov, Tanzila Rahman, Rosemary Kaufman, Christine Fregeau, Vikki Spaulding, Michelle Priess, Kristen Legendre, Sarah Jaffe, Dhruvkumar Upadhyay, Anirudh Singh, Chang-Ai Xu, Kristin Krukenberg, Yan Zhang, Yassine Ezzyat, Dorothée Saddier Axe, Michelle R. Kuhne, Michael A. Meehl, Donald R. Shaffer, Brian M. Weist, Dmitri Wiederschain, Fabien Depis, Monica Gostissa   +28 more
doaj   +1 more source

Anti-tumor effect of mitochondrial targeted small molecule IR-780 on cisplatin-resistant bladder cancer cells

Di-san junyi daxue xuebao, 2021
Objective To study the anti-tumor effect of IR-780, a mitochondrial targeting small molecule, on cisplatin-resistant T24 cell line (T24/DPP). Methods T24/DPP cell line was constructed by repeated and discontinuous stimulation of T24 cells with cisplatin.
HUANG Yuandi, SHEN Chongxing, LI Jinjin, FANG Qiang, ZHI Yi   +4 more
doaj   +1 more source

Red and Infrared Low-Level Laser Therapy Prior to Injury with or without Administration after Injury Modulate Oxidative Stress during the Muscle Repair Process. [PDF]

PLoS ONE, 2016
INTRODUCTION:Muscle injury is common among athletes and amateur practitioners of sports. Following an injury, the production of reactive oxygen species (ROS) occurs, which can harm healthy muscle fibers (secondary damage) and delay the repair process ...
Beatriz Guimarães Ribeiro, Agnelo Neves Alves, Lucas Andreo Dias Dos Santos, Tatiane Matarazzo Cantero, Kristianne Porta Santos Fernandes, Danielle da Silva Dias, Nathalia Bernardes, Kátia De Angelis, Raquel Agnelli Mesquita-Ferrari   +8 more
doaj   +1 more source

FISIOLOGÍA DE LA GERMINACIÓN DE Rhodophiala bifida

Fave: Sección Ciencias Agrarias, 2021
Nuestro objetivo es contribuir al conocimiento de las características fisiológicas básicas de la germinación y perduración de semillas de Rodophiala bifida.
M. C. ACOSTA, M. L. ALCARAZ, R. L. SCARAMUZZINO, V. T. MANFREDA   +3 more
doaj   +1 more source

Response of Tannat (Vitis vinifera L.) to pre-flowering leaf removal in a humid climate

OENO One, 2021
The aim of this study was to test the effect of pre-flowering leaf removal (PFD) on grape sanitary status, yield, source-sink balance and berry composition.
Leandro Arrillaga, Gerardo Echeverría, Bruno Izquierdo, Juan José Rey, Alejandra Pallante, Milka Ferrer   +5 more
doaj   +1 more source

The Oxidative and Color Stability of Beef from Steers Fed Pasture or Concentrate during Retail Display

Animals, 2023
Beef production in Uruguay is based on pasture (~85%) or concentrate (~15%), resulting in differences in meat quality. The objective of this study was to compare the oxidative stability and color of beef from these two systems during refrigerated retail ...
Alejandra Terevinto, María Cristina Cabrera, Fernanda Zaccari, Ali Saadoun   +3 more
doaj   +1 more source

Sodium Valproate Incompatibility with Parenteral Nutrition Admixtures—A Risk to Patient Safety: An In Vitro Evaluation Study

Pharmaceutics, 2022
Epilepsy is defined as a group of concerning problems related to the nervous system; its defining feature is a predisposition to epileptic seizures. The frequency of seizures in intensive care units (ICU) ranges from 3.3% to 34%, and ICU antiepileptic ...
Ludwika Piwowarczyk, Szymon Tomczak, Patryk Antkowiak, Anna Jelińska, Maciej Stawny   +4 more
doaj   +1 more source

Dye-loaded mesoporous polydopamine nanoparticles for multimodal tumor theranostics with enhanced immunogenic cell death

Journal of Nanobiotechnology, 2021
Background Tumor phototherapy especially photodynamic therapy (PDT) or photothermal therapy (PTT), has been considered as an attractive strategy to elicit significant immunogenic cell death (ICD) at an optimal tumor retention of PDT/PTT agents ...
Ying Tian, Muhammad Rizwan Younis, Yuxia Tang, Xiang Liao, Gang He, Shouju Wang, Zhaogang Teng, Peng Huang, Longjiang Zhang, Guangming Lu   +9 more
doaj   +1 more source

All-in-One Pediatric Parenteral Nutrition Admixtures with an Extended Shelf Life—Insight in Correlations between Composition and Physicochemical Parameters

Pharmaceutics, 2021
The administration of three-in-one parenteral nutrition (PN) admixtures to pediatric patients requires special consideration, specifically concerning quality and physicochemical stability. The introduction of a new parenteral amino acid solution into the
Aleksandra Gostyńska, Joanna Starkowska, Paulina Sobierajska, Anna Jelińska, Maciej Stawny   +4 more
doaj   +1 more source

Methyl 2-amino-5-iso­propyl-1,3-thia­zole-4-carboxyl­ate [PDF]

, 2004
The title compound, C8H12N2O2S, forms a supramolecular network based on N-HN hydrogen-bonded centrosymmetric dimers that are linked in turn by N-HO ...
Kennedy, Alan R., Khalaf, Abedawn I., Suckling, Colin J., Waigh, Roger D.   +3 more
core   +1 more source