Results 171 to 180 of about 1,025,248 (303)

Lymphatic Abnormalities in Noonan Syndrome Extend Beyond Clinically Apparent Disease

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Lymphatic disease represents a well‐described manifestation of Noonan syndrome (NS), yet the full phenotypic spectrum remains incompletely characterized, especially in asymptomatic individuals. We conducted a cross‐sectional study including 10 individuals with NS (four with peripheral lymphedema and six without) and 10 age‐ and sex‐matched ...
Inger Norlyk Sheyanth, Benjamin Kelly, Sheyanth Mohanakumar, Steffen Ringgaard, Yoav Dori, Irene Kibæk Nielsen, Uffe Birk Jensen, Vibeke Elisabeth Hjortdal   +7 more
wiley   +1 more source

Engineering Nanoemulsions to Maximize NIR‐II Fluorescence and Preserve Photothermal Performance of a Novel Boron Difluoride Formazanate Dye

Angewandte Chemie, EarlyView.
An oil‐in‐water nanoemulsion transforms a boron difluoride formazanate (BDF) dye into a dual‐modal imaging‐guided theranostic agent (BDF‐NE). Its nonpolar oil core maximizes NIR‐II fluorescence while maintaining strong photoacoustic contrast to guide photothermal therapy with high photostability and 66.8% photothermal conversion efficiency, achieving ...
Nahyun Kwon, Francis L. Buguis, Theo Husby, Suhjung Chun, Dongling Zhang, Jiaze Wu, Benjamin Rehl, Binbing Ling, Umar Iqbal, Melissa Washington, Angie Verner, Kai Huang, Juan Chen, Joe B. Gilroy, Gang Zheng   +14 more
wiley   +2 more sources

Effective plasmonic enhancement of up-conversion photoluminescence from α-NaGdF₄:Yb³⁺,Er³⁺ nanoparticles by gold dendrites. [PDF]

Sci Rep
Pham NBT, Burko A, Murashka V, Laputsko D, Bandarenka H, Dauletbekova A, Mamatkulov K, Arzumanyan G.   +7 more
europepmc   +1 more source

Co‐Occurring Non‐Cardiac Congenital Anomalies Among Cases With Congenital Heart Defects

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Cases with congenital heart defects (CHD) often have other associated anomalies. The aim of this investigation was to assess the prevalence and the types of co‐occurring anomalies in CHD in a well‐defined population. The anomalies co‐occurring with CHD were ascertained in all live births, stillbirths and terminations of pregnancy for fetal ...
Claude Stoll, Yves Alembik, Marie‐Paule Roth   +2 more
wiley   +1 more source

Inverse Restriction Site-Associated DNA Sequencing (iRAD-seq). [PDF]

Bio Protoc
Chen P, Zhou S, Wang H, Gu J, Li Y, Chang Y.   +5 more
europepmc   +1 more source

Nonviral Gold Nanoparticle‐Mediated Delivery of CRISPR‐Cas9 Ribonucleoprotein and Long DNA Transgenes Into Primary Blood Cells

Advanced NanoBiomed Research, EarlyView.
CRISPR/Cas9 has revolutionized the field of gene therapy, but delivery remains an outstanding issue. We propose a nonviral gold‐nanoparticle platform for co‐delivery of CRISPR/Cas9 ribonucleoprotein and long 2.1 kilobase dsDNA transgene constructs. This CRISPR‐AuNP is inexpensive to produce and mediate gene editing and DNA delivery in T cells and CD34+
Rachel A. Cunningham, Karthikeya S. V. Gottimukkala, Daniel D. Lane, Katrina Poljakov, Patricia Lipson, Mark R. Enstrom, Alessandro Rizzi, Aude G. Chapuis, Jennifer E. Adair   +8 more
wiley   +1 more source

Photoinduced Radical Cations Enable Anti-Kasha Emission in a Pyrene-Based Azacationic Ladder Polymer. [PDF]

Small Sci
Nunes Barradas PD, Scherf U, Seixas de Melo JS.   +2 more
europepmc   +1 more source

Oxytocin‐ und Vasopressin‐Photosonden zur Entschlüsselung der Neuropeptid‐Signalgebung mit hoher räumlicher und zeitlicher Präzision

Angewandte Chemie, EarlyView.
Neue biokompatible Oxytocin‐ und Vasopressin‐Photosonden mit modernsten Photocages. Diese Photosonden sind inaktiv und können mit spezifischen Lichtwellen entschützt werden, was eine Rezeptoraktivierung mit hoher zeitlicher und räumlicher Kontrolle ermöglicht. Abbildung erstellt mit https://BioRender.com ZUSAMMENFASSUNG Das Oxytocin/Vasopressin (OT/VP)
Konstantin Raabe, Predrag Kalaba, Xuan Ling Hilary Yong, Greta Crudeli, Sarah Melzer, Erik Keimpema, Victor Anggono, Markus Muttenthaler   +7 more
wiley   +1 more source

Ein Dithio‐Vinylthio‐C2‐Synthon, das kristalline und lumineszierende, schwefelhaltige Polymere ermöglicht

Angewandte Chemie, EarlyView.
Die Umsetzung von CaC2 zu einem modularen C2‐Baustein ermöglicht die Synthese eines α,ω‐Bis(vinylthio)‐Monomers sowie dessen Weiterumsetzung zu kristallinen, sequenzdefinierten, schwefelfunktionalisierten Polymere. Dichte Thioether‐Cluster induzieren nichtkonventionelle Lumineszenz und ermöglichen eine präzise Kontrolle der Struktur‐Eigenschafts ...
Bercis Pektas, Cuong M. Q. Le, Samar Hajjar‐Garreau, Simon Gree, Hatice Mutlu   +4 more
wiley   +1 more source

Manganese-based nanotheranostics synergizing photothermal-chemotherapy for liposarcoma treatment. [PDF]

RSC Adv
Zhan W, Du S, Zhu T, Liu Y, Li L, Gao Y, Lu Y, Wang W.   +7 more
europepmc   +1 more source