Results 61 to 70 of about 86,142 (285)

Trends in the utilization, expenditure and costs of noninsulin glucose‐lowering drugs in the Medicaid population: Steady increases in glucagon‐like peptide‐1 receptor agonist and sodium–glucose transporter‐2 inhibitor use, prices and expenditure

British Journal of Clinical Pharmacology, EarlyView.
Aims This study aimed to analyse changes in the utilization, expenditure and average cost of noninsulin glucose‐lowering drugs (GLDs) between 2008 and 2023. Methods This was a retrospective observational study of 2008–2023 data from the National Medicaid State Drug Utilization database.
Rawan O. Almadfaa
wiley   +1 more source

Usefulness of an Image Fusion Model Using Three-Dimensional CT and MRI with Indocyanine Green Fluorescence Endoscopy as a Multimodal Assistant System in Endoscopic Transsphenoidal Surgery

International Journal of Endocrinology, 2015
Purpose. We investigate the usefulness of multimodal assistant systems using a fusion model of preoperative three-dimensional (3D) computed tomography (CT) and magnetic resonance imaging (MRI) along with endoscopy with indocyanine green (ICG ...
Akihiro Inoue, Takanori Ohnishi, Shohei Kohno, Naoya Nishida, Yawara Nakamura, Yoshihiro Ohtsuka, Shirabe Matsumoto, Shiro Ohue   +7 more
doaj   +1 more source

Radiation-induced laryngeal angiosarcoma: Case report

Otolaryngology Case Reports, 2018
Head and neck angiosarcoma (AS) is extremely rare. We report the fourth case report of radiation-induced laryngeal AS. The patient is a 73-year-old man with a past medical history of radiation treatment for hypopharyngeal cancer.
Hiroyuki Hanakawa, Nobuya Monden, Kaori Hashimoto, Aiko Oka, Isao Nozaki, Norihiro Teramoto, Susumu Kawamura   +6 more
doaj   +1 more source

Model‐informed precision dosing of carboplatin in cancer patients by leveraging myelosuppression data from electronic health records

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims This study aimed to develop and validate a population pharmacokinetic‐pharmacodynamic (pop‐PK‐PD) model to describe carboplatin‐induced myelosuppression in cancer patients and support dose individualization. Methods Data from 580 cancer patients treated with carboplatin at Amsterdam UMC between 2019 and 2022 were used for model ...
Alessandro De Carlo, Elena Maria Tosca, Mirjam Crul, Tim Schutte, Lia van Zuijlen, Idris Bahce, Medhat M. Said, Jan Buter, Harmen Huls, Paolo Magni, Imke Bartelink   +10 more
wiley   +1 more source

Analysis of interstitial lung disease in pharmacovigilance databases: Coding challenges and interpretation biases—An update

British Journal of Clinical Pharmacology, EarlyView.
Aim Clinically, interstitial lung disease (ILD) is a heterogeneous group of respiratory disorders. Due to their low incidence, pharmacovigilance database analysis is useful to detect them. Precise diagnosis is challenging as well as coding in these databases. Query criteria are among the key elements for a good signal detection.
Romane Freppel, Adeline Benis, Philippe Bonniaud, Jean‐Luc Faillie, Aurélie Grandvuillemin   +4 more
wiley   +1 more source

Developing medication independence: The experience of UK teenagers

British Journal of Clinical Pharmacology, EarlyView.
Aims There is a progression through childhood from being provided medications by caregivers to having to take responsibility for medications yourself, but little is known about when the transition of adolescents managing medicines begins. The aim of this study was to obtain a cross‐sectional sample of UK adolescents and when they become independent ...
Holly Hutchins, Charlotte King, Louis Bioletti, Tsegay Gebru, Alder Hey Research Ambassadors, Daniel B. Hawcutt   +5 more
wiley   +1 more source

On the 𝑞-Genocchi Numbers and Polynomials with Weight 𝛼 and Weak Weight 𝛽

Journal of Applied Mathematics, 2012
We construct a new type of 𝑞-Genocchi numbers and polynomials with weight 𝛼 and weak weight 𝛽∶𝐺(𝛼,𝛽)𝑛,𝑞,𝐺(𝛼,𝛽)𝑛,𝑞(𝑥), respectively. Some interesting results and relationships are obtained.
J. Y. Kang, H. Y. Lee, N. S. Jung
doaj   +1 more source

Biochemical and histological evidence of deteriorated bioprosthetic valve leaflets: the accumulation of fibrinogen and plasminogen

Biology Open, 2018
Calcification of bioprosthetic valves (BVs) implanted in aortic position can result in gradual deterioration and necessitate aortic valve replacement. The molecular mechanism of calcium deposition on BV leaflets has been investigated, but remains to be ...
Tomohisa Sakaue, Hirotomo Nakaoka, Fumiaki Shikata, Jun Aono, Mie Kurata, Teruyoshi Uetani, Mika Hamaguchi, Ai Kojima, Shunji Uchita, Takumi Yasugi, Haruhiko Higashi, Jun Suzuki, Shuntaro Ikeda, Jitsuo Higaki, Shigeki Higashiyama, Hironori Izutani   +15 more
doaj   +1 more source

Highly Potent Fluorogenic Ligands for Triplex DNA: 5‐Substituted 2‐(Naphthalen‐2‐yl)‐4H‐Chromen‐4‐Ones

Chemistry – A European Journal, EarlyView.
5‐Substituted 2‐(naphthalen‐2‐yl)‐4H‐chromen‐4‐ones are reported as a novel class of highly potent and selective triplex DNA ligands. These ligands induce triplex formation at submicromolar concentrations and inhibit enzymatic activity via ligand‐mediated triplex formation.
Nghia Tran, Landy Gu, Krege M. Christison, Kalee Thao, Liang Xue   +4 more
wiley   +1 more source

Some Relations of the Twisted q-Genocchi Numbers and Polynomials with Weight α and Weak Weight β

Abstract and Applied Analysis, 2012
Recently many mathematicians are working on Genocchi polynomials and Genocchi numbers. We define a new type of twisted q-Genocchi numbers and polynomials with weight 𝛼 and weak weight 𝛽 and give some interesting relations of the twisted q-Genocchi ...
J. Y. Kang, H. Y. Lee, N. S. Jung
doaj   +1 more source