Results 51 to 60 of about 2,959,250 (293)
Molecular Oncology, EarlyView.The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld +7 more
wiley +1 more source
Firms Growth Dynamics, Competition and Power Law Scaling
, 2002 We study the growth dynamics of the size of manufacturing firms considering competition and normal distribution of competency. We start with the fact that all components of the system struggle with each other for growth as happened in real competitive ...
Campanha, Jose R., Gupta, Hari M.
core +1 more source
Investigating Energy Use, Environment Pollution, and Economic Growth in Developing Countries
Environmental and Climate Technologies, 2020 Attaining continuous economic growth entails special consideration of energy sector and the environment. Compliance with this purpose may be more intricate in the uncertain milieu of developing countries.
Abdollahi Hooman
doaj +1 more source
Generalized Trust, Helpfulness, Fairness and Growth in European Countries A Revised Analysis
Comparative Economic Research, 2022 This research is an attempt to assess the impact of trust, helpfulness, and fairness on economic growth in Europe. The first part of the paper highlights the concept of social capital and the related concept of trust, while the second part gives an ...
Jan Jacek Sztaudynger +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Dinaciclib blocks CDK12 activity, leading to downregulation of BRCA1, and probably other proteins involved in homologous recombination, promoting nonhomologous end joining. In this scenario, the presence of ionising radiation triggers a p53‐dependent senescent response that yields increased radiosensitivity. Pan‐cyclin‐dependent‐kinase (CDK) inhibitors
Natalia García Flores +14 more
wiley +1 more source
An Investigation of Corruption and Economic Growth Nexus: Some Evidence from D-8 Countries [PDF]
Faslnāmah-i Pizhūhish/Nāmah-i Iqtisādī, 2014 This study investigates the potential threshold effects in the relationship between corruption control index and GDP growth for the D-8 countries with the presence of other variables, including education expenditures, government consumption expenditures,
Hasan Heidari +3 more
doaj
Multi‐omics profiling reveals key factors involved in Ewing sarcoma metastasis
Molecular Oncology, EarlyView.Using a mouse model that recapitulates the spread of tumor cells within the body, we have profiled paired tumors and metastasis samples using a multiomics approach combining different layers of biological information. We identified key genes that drive metastasis in Ewing sarcoma.
Mariona Chicón‐Bosch +11 more
wiley +1 more source
Molecular Oncology, EarlyView.In molecular cancer diagnostics, comprehensive genomic profiling (CGP) is going to replace the small NGS panels since it provides all clinically relevant somatic variants as well as genomic biomarkers with clinical value. Here, we compared two CGP assays and demonstrate that the choice for diagnostic implementation will depend on the specific ...
Guy Froyen +17 more
wiley +1 more source
DETERMINANTS OF FEMALE WORKERS ON ECONOMIC GROWTH
Jurnal Ekonomi dan Bisnis Airlangga, 2021 Introduction: This study aims to find out what influences the Provincial Economic Growth in the Java Island if seen from female workers through the some variables, namely life expectancy of female, female's income contributions, and female as ...
Mohammad Ilham Azizi
doaj +1 more source
Identification of inhibitors of the Salmonella FraB deglycase, a drug target
FEBS Open Bio, EarlyView.A high‐throughput screen was used to identify inhibitors of Salmonella FraB, a drug target. Characterization of top hits (identified after an additional counter screen) revealed that some triazolidines, thiadiazolidines, and triazolothiadiazoles are mixed‐type inhibitors of FraB.
Jamison D. Law +6 more
wiley +1 more source