Results 141 to 150 of about 20,472,724 (278)

Surface Topography and Tolerance Quality Evaluation of Polymer Gears Using Non-Contact 3D Scanning Method. [PDF]

Materials (Basel)
Muratović E, Muminović AJ, Gierz Ł, Smailov I, Sydor M, Dizdarević E, Pervan N, Delić M.   +7 more
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

80 Rappen? - Nie! / 80 centimes? - Jamais! [PDF]

Bulletin des Médecins Suisses, 2000
openaire   +2 more sources

Deficit-irrigation management for sustainable grape production (Vitis vinifera L.): different regimes to assess yield and berry quality under arid conditions. [PDF]

Sci Rep
El-Salhy AM, Salem EH, Mohamed MMA, Hussein AS.   +3 more
europepmc   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Size-dependent cryoprotective effects of curcumin nanoparticles on DNA integrity and motility in cryopreserved Angora buck sperm. [PDF]

Front Vet Sci
Öztürk AE, Sarıözkan S, Bodu M, Atay YE, Şahin D, Korkmaz O, Öztürk C, Kılınç Z, Mirioglu M, Temur N, Teǧiş İY, Şanlı M, Bucak MN, Öçsoy İ.   +13 more
europepmc   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Olezarsen in Hypertriglyceridemia With High Cardiac Risk: A GRADE-Assessed Meta-Analysis of Randomized Trials With Trial Sequential Evidence. [PDF]

Endocrinol Diabetes Metab
Emara A, Awashra A, Aboeldahab H, Gadelmawla AF, Abdul-Hafez HA, Alharran AM, Alsubaiei AA, AlRumaihi MJ, Albuhmaid SA, Shubietah A.   +9 more
europepmc   +1 more source

80\u27s Woman [PDF]

, 1982
Thomas, Ann
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source