Results 61 to 70 of about 4,455,241 (287)
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling
FEBS Open Bio, EarlyView.Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang +7 more
wiley +1 more source
The Indian Journal of Agricultural SciencesThe present study was carried out from 2018 to 2024 at ICAR-Research Complex for Eastern Region, Patna, Bihar to evaluate eight farming system models [Field crops (FC) alone; FC + Fish + Duck; FC + Fish + Poultry; FC + Fish + Cattle; FC + Fish ...
SANJEEV KUMAR +9 more
doaj +1 more source
Corporate Social and Financial Performance: Empirical Evidence from American Companies [PDF]
, 2013 The objective of this study is to address the issue of the relationship between corporate social and financial performance by moderating company size and financial leverage.with the use of type of industry as control variable.
Fauzi, Hasan
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, 2017 The dynamics of thermal and non-thermal lattice deformation of nanometer thick polycrystalline aluminum film has been studied by means of femtosecond (fs) time-resolved electron diffraction.
Cao, Jianming +5 more
core +1 more source
FEBS Open Bio, EarlyView.We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan +6 more
wiley +1 more source
Femtosecond Pump-Probe Diagnostics Of Preformed Plasma Channels [PDF]
, 2004 We report on recent ultrafast pump-probe experiments 28 in He plasma waveguides using 800 nm, 80 fs pump pulses of 0.2 x 1018 W/cm2 peak guided intensity, and single orthogonally-polarized 800 nm probe pulses with similar to0.1% of pump intensity.
Debus, A. +5 more
core +1 more source
SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1
FEBS Open Bio, EarlyView.Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl +13 more
wiley +1 more source
Cytologic characteristics of adenoid cystic carcinoma of the cervix uteri: case report [Citološke karakteristike adenoid cističnog karcinoma vrata maternice: prikaz slučajeva] [PDF]
, 2010 Adenoid cystic carcinoma is a rare malignancy, usually found in the salivary glands, although this unusual tumor can be found at other sites of the body.
Babić, Damir +6 more
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