Results 81 to 90 of about 11,599,832 (322)

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Effect of iron content on β → α phase transformation behavior of Ti-5Al-xFe (x = 1, 2.5, 4) alloys during continuous cooling

open access: yesJournal of Materials Research and Technology, 2019
We investigated the effect of Fe content on the β → α phase transformation behavior of Ti-5Al-xFe (x = 1, 2.5, 4) alloys during continuous cooling. The presence of Fe delayed long-range diffusional phase transformation, thus facilitating diffusionless ...
Gyeong Ryeong Bak   +4 more
doaj   +1 more source

The Great Chicago Fire- October 8-10, 1871 [PDF]

open access: yes, 2006
Essay on the Great Chicago Fire of 1871.unpublishednot peer ...
Groves, Adam
core  

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

Upright-Standing SnO2 Nanosheets Glazed CdSe Nanocrystallites: High Photocurrent Generating Photoelectrochemical Cells

open access: yesInternational Journal of Electrochemical Science, 2013
Efficient charge separation in photoelectrochemical cell composed of solution-processed SnO2 nanosheets (NSs)-CdSe nanocrystallites (NCs), is investigated.
Sambhaji S. Bhande   +5 more
doaj   +1 more source

Shell-model half-lives for r-process waiting point nuclei including first-forbidden contributions

open access: yes, 2013
We have performed large-scale shell-model calculations of the half-lives and neutron-branching probabilities of the r-process waiting point nuclei at the magic neutron numbers N=50, 82, and 126.
Caurier, E.   +5 more
core   +3 more sources

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

open access: yesFEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz   +9 more
wiley   +1 more source

Service Design within a Product Design teaching programme: generating benefits to education as well as service organisations. [PDF]

open access: yes, 2010
Developing service design within the product design programme at Glasgow School of Art, involved exploring areas of commonality between product and service design and the parallel skills that can be applied to both.
Bailey, Stuart
core  

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy