Results 31 to 40 of about 1,024,015 (309)
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Advancing green and digital transition is a key topic on Europe’s agenda, aligned with the UN’s SDG goals. In this context, this study investigates existing support tools and programs for upskilling digital, green, and entrepreneurial (DGE) competences ...
Ivana Ninčević Pašalić +2 more
doaj +1 more source
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Radiofrequency electromagnetic fields (EMF) are subjected to a public perceived risk of adverse effects, and results from many epidemiology studies were largely inconclusive.
Abel B. Olorunsola +4 more
doaj +1 more source
Paradigma Pengembangan Industri Peternakan Menuju Swasembada dan Ketahanan Pangan (Daging)di Propinsi Lampung [PDF]
The livestock industry as one of the economic sectors, there is a potential and strategic functions to be developed, as a source of regional and communities income. including for the development of small and medium enterprises (SMEs).
Machrus, M. (Mohammad)
core
How can SMEs benefit from big data? Challenges and a path forward [PDF]
Big data is big news, and large companies in all sectors are making significant advances in their customer relations, product selection and development and consequent profitability through using this valuable commodity. Small and medium enterprises (SMEs)
Ahlemeyer-Stubbe +28 more
core +2 more sources
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Research demonstrates a predominantly negative public perception of the oil and gas (O&G) industry, regardless of initiatives created to minimize the environmental impact.
Sourojeet Chakraborty +4 more
doaj +1 more source
Critical Infrastructure, Terrorism, and the Chemical Facility Anti-Terrorism Standards: The Need for Collaboration [PDF]
In response to 9/11 and the increasing concerns over chemical sector security, Congress gave the Department of Homeland Security (DHS) the authority to regulate the safety and security of U.S. chemical facilities. In April of 2007, DHS passed the interim
Rooijakkers, Maria, Sadiq, Abdul-Akeem
core
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source

