Results 31 to 40 of about 1,024,015 (309)

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Evaluating upskilling tools for digital, green, and entrepreneurial competences: A multicriteria approach to advancing Europe’s green and digital transition

open access: yesCroatian Operational Research Review
Advancing green and digital transition is a key topic on Europe’s agenda, aligned with the UN’s SDG goals. In this context, this study investigates existing support tools and programs for upskilling digital, green, and entrepreneurial (DGE) competences ...
Ivana Ninčević Pašalić   +2 more
doaj   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Temporal variation of exposure from radio-frequency electromagnetic fields around mobile communication base stations

open access: yesScientific African, 2021
Radiofrequency electromagnetic fields (EMF) are subjected to a public perceived risk of adverse effects, and results from many epidemiology studies were largely inconclusive.
Abel B. Olorunsola   +4 more
doaj   +1 more source

Paradigma Pengembangan Industri Peternakan Menuju Swasembada dan Ketahanan Pangan (Daging)di Propinsi Lampung [PDF]

open access: yes, 2014
The livestock industry as one of the economic sectors, there is a potential and strategic functions to be developed, as a source of regional and communities income. including for the development of small and medium enterprises (SMEs).
Machrus, M. (Mohammad)
core  

How can SMEs benefit from big data? Challenges and a path forward [PDF]

open access: yes, 2016
Big data is big news, and large companies in all sectors are making significant advances in their customer relations, product selection and development and consequent profitability through using this valuable commodity. Small and medium enterprises (SMEs)
Ahlemeyer-Stubbe   +28 more
core   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Student perception of sustainability in industry: a case study in an undergraduate petroleum processing course

open access: yesFrontiers in Education
Research demonstrates a predominantly negative public perception of the oil and gas (O&G) industry, regardless of initiatives created to minimize the environmental impact.
Sourojeet Chakraborty   +4 more
doaj   +1 more source

Critical Infrastructure, Terrorism, and the Chemical Facility Anti-Terrorism Standards: The Need for Collaboration [PDF]

open access: yes, 2014
In response to 9/11 and the increasing concerns over chemical sector security, Congress gave the Department of Homeland Security (DHS) the authority to regulate the safety and security of U.S. chemical facilities. In April of 2007, DHS passed the interim
Rooijakkers, Maria, Sadiq, Abdul-Akeem
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

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