Results 161 to 170 of about 77,307 (222)

Unveiling Candidate Markers for Drug Resistance or Synthetic Lethality in Cervical Cancer: Integrative Analysis of Genetic and Pharmacoprofiling

open access: yesCancer Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Introduction Systemic cervical cancer management continues to be challenging. Numerous chemotherapies have been approved, but predicting response is difficult due to the lack of biomarkers. Here, we analyze the genetic and protein profiles of 20 cervical cancer cell lines (CCCLs) and explore their correlation with drug response patterns to ...
Suzy Scholl   +10 more
wiley   +1 more source

Critical role of keratinocytes and protease‐activated receptor 2 in secondary lymphedema development

open access: yesClinical and Translational Medicine, Volume 16, Issue 6, June 2026.
Activated keratinocytes play an important role in the early stage of the pathophysiology of secondary lymphedema through PAR2 signaling. Lymphatic injury‐induced protease activation stimulates keratinocyte PAR2 signaling, driving hyperkeratosis and Th2 inflammation, which can be therapeutically attenuated by teriflunomide. Abstract Background Secondary
Hyeung Ju Park   +18 more
wiley   +1 more source

Creek‐imposed gradients reshape plant allometric traits and sediment retention in a salt marsh

open access: yesEcosphere, Volume 17, Issue 6, June 2026.
Abstract Tidal creeks impose strong hydrological and geomorphic gradients that shape plant traits and sediment dynamics in salt marshes. However, how creek‐imposed gradients reorganize plant allometric strategies and how these trait shifts regulate sediment retention remain poorly quantified.
Guang‐Cheng Cheng   +2 more
wiley   +1 more source

A Hybrid Deep Learning Approach With Multimodal Neurocognitive Features and Quantum Optimization for Early Detection of Alzheimer's Disease and Related Dementias

open access: yesEngineering Reports, Volume 8, Issue 6, June 2026.
A hybrid deep learning framework integrating convolutional–transformer networks and global gated attention is proposed for early dementia detection using multimodal MRI and speech data. Quantum marine predator optimization enhances classification performance, achieving superior accuracy and robustness compared with existing state‐of‐the‐art methods ...
R. Anandan   +3 more
wiley   +1 more source

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