Results 31 to 40 of about 513,872 (297)

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

open access: yesFEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino   +7 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

On the classical r-matrix structure of the rational BCn Ruijsenaars–Schneider–van Diejen system

open access: yesNuclear Physics B, 2015
In this paper, we construct a quadratic r-matrix structure for the classical rational BCn Ruijsenaars–Schneider–van Diejen system with the maximal number of three independent coupling parameters.
B.G. Pusztai
doaj   +1 more source

Variation of tensile strength and elastic limit due to tempering at low temperature on quenched medium carbon steel

open access: yesNihon Kikai Gakkai ronbunshu, 2021
Although elastic limit and tensile strength are essential for mechanical strength design, the measurement of high hardness materials is a challenge due to their sensitivity on notches.
Junzo SHIMBE   +3 more
doaj   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

open access: yesFEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Review: Hans Eric Stolten (ed.): History Making and Present Day Politics. The Meaning of Collective Memory in South Africa (2007) Buchbesprechung: Hans Eric Stolten (Hrsg.): History Making and Present Day Politics. The Meaning of Collective Memory in South Africa (2007)

open access: yesAfrica Spectrum, 2009
Review of the edited volume: Hans Eric Stolten (ed.): History Making and Present Day Politics. The Meaning of Collective Memory in South Africa, Uppsala: Nordic Africa Institute 2007, ISBN 978-91-7106-581-0, 376 pages.
Rita Schäfer
doaj  

Neutralino dark matter and other LHC predictions from quasi Yukawa unification

open access: yesNuclear Physics B, 2015
We explore the dark matter and LHC implications of t−b−τ quasi Yukawa unification in the framework of supersymmetric models based on the gauge symmetry G=SU(4)c×SU(2)L×SU(2)R.
Qaisar Shafi   +2 more
doaj   +1 more source

Modeling of hydraulic support system for large structures

open access: yesNihon Kikai Gakkai ronbunshu, 2021
In the control of a large structure, hydraulic equipment is often used because it requires a large output. In this study, we focus on the telescope as an example of a large structure, and model its hydraulic support system and analyze its characteristics
Tomoya HATTORI   +5 more
doaj   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

open access: yesFEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen   +6 more
wiley   +1 more source

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