Results 101 to 110 of about 11,473,789 (281)

Real World Effectiveness and Tolerability of Novel Monoclonal Antibodies and Rituximab for NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT In this multicenter retrospective cohort study of 135 people with aquaporin‐4 IgG+ neuromyelitis optica spectrum disorder (NMOSD), some of whom were exposed to multiple therapies, we evaluated the effectiveness and tolerability of rituximab (n = 111) and novel monoclonal antibodies (nMAbs): eculizumab (n = 9), inebilizumab (n = 23), and ...
Zarmina Javed, Mengke Du, Mary Rensel, Le H. Hua, Carrie M. Hersh, Justin R. Abbatemarco, Devon S. Conway, Daniel Ontaneda, Jeffrey A. Cohen, Amy Kunchok   +9 more
wiley   +1 more source

Long‐Term Evaluation of Givinostat in Duchenne Muscular Dystrophy, and Natural History Comparisons

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives This ongoing, open‐label extension study is evaluating the long‐term safety, tolerability, and efficacy of givinostat, a Class I and II histone deacetylase inhibitor, in patients with Duchenne muscular dystrophy (DMD). Methods The recruited patients completed one of two prior clinical studies (one Phase 2 and one Phase 3 [EPIDYS ...
Craig M. McDonald, Michela Guglieri, Dragana Vučinić, Gyula Acsadi, John F. Brandsema, Claudio Bruno, Erika L. Finanger, Amy Harper, Mercedes Lopez Lobato, Riccardo Masson, Nuria Muelas, Francina Munell, Yoram Nevo, Yann Péréon, Han Phan, Valeria A. Sansone, Mariacristina Scoto, Tracey Willis, Richard S. Finkel, Krista Vandenborne, Sara Cazzaniga, Silvia Montrasio, Federica Alessi, Paolo Bettica, Eugenio Mercuri, for the Givinostat Study 51 Investigators, the Cooperative International Neuromuscular Research Group (CINRG) Duchenne Natural History Study (DNHS) Investigators, the ImagingDMD Investigators, Enrico Bertini, Giacomo Pietro Comi, Eugenio Maria Mercuri, Giuseppe Vita, Sonia Messina, Claudio Bruno, Riccardo Masson, Valeria Sansone, Nathalie Goemans, Liesbeth De Waele, Laurent Servais, Teresa Gidaro, Odile Boespflug‐Tanguy, Yann Péréon, Jessika Johannsen, Astrid Blaschek, Ulrike Schara‐Schmidt, Erik Niks, Imelda de Groot, Saskia Houwen‐van Opstal, Andres Nascimento, Juan Jesus Vilchez, Nuria Muelas, Francina Munell, Marcos Madruga Garrido, Mercedes Lopez Lobato, Michaela Guglieri, Tracey Willis, Stefan Spinty, Daniel Hawcutt, Mariacristina Scoto, Jean K. Mah, Laura McAdam, Kathryn Selby, Katherine Mathews, Craig McDonald, Craig Zaidman, Barry Byrne, John Brandsema, Gyula Acsadi, Chamindra Laverty, Amy Harper, Erika Finanger, Han Phan, Yoram Nevo, Vedrana Milic Rasic, Dragana Vucinic   +74 more
wiley   +1 more source

Keller–Segel type approximation for nonlocal Fokker–Planck equations in one-dimensional bounded domain

European Journal of Applied Mathematics
Numerous evolution equations with nonlocal convolution-type interactions have been proposed. In some cases, a convolution was imposed as the velocity in the advection term.
Hideki Murakawa, Yoshitaro Tanaka
doaj   +1 more source

Analysis of a fractional-order model for acute and chronic hepatitis-B transmission with Mittag-Leffler kernels

Computational and Mathematical Biophysics
This study explores the dynamic characteristics of a fractional-order model for the hepatitis B virus (HBV) epidemic. We present the existence, uniqueness, and Ulam-Hyers stability of solutions for a fractional-order HBV model utilizing the Atangana ...
Wiah Eric Neebo, Crankson Monica Veronica, Addor John Awuah, Moore Stephen Edward   +3 more
doaj   +1 more source

Longitudinal Relationship Between Pain and Depression in People With Inflammatory Arthritis: A Narrative Review

Arthritis Care &Research, EarlyView.
As many patients with inflammatory arthritis (IA) have chronic pain, understanding how to best assess and manage pain in IA is a priority. Comorbid depression is prevalent in adults with IA, affecting 15% to 39% of people. Although pain and depression are thought to be associated in IA, this concept is largely based on cross‐sectional data.
Natasha Cox, Saeed Farooq, Helen Twohig, Ian C. Scott   +3 more
wiley   +1 more source

Perwityna, „krystaliczna metamfetamina” – nowe zagrożenie na polskiej scenie narkotykowej

Psychiatria i Psychologia Kliniczna, 2012
Terminem perwityna określa się w Europie Środkowej metamfetaminę wyprodukowaną nielegalnie z efedryny lub pseudoefedryny, jako prekursora. Od kilkunastu lat notuje się w niektórych krajach europejskich zwiększone zainteresowanie używaniem tej ...
Anna Dietrich-Muszalska
doaj  

Ageism in Rheumatology: The Health Care Professional's Perspective

Arthritis Care &Research, EarlyView.
Objective Ageism (age‐based stereotypes, prejudice, or discrimination) is prevalent and linked to prolonged disability and reduced lifespan in older adults. Little is known about ageism within rheumatology. This study explores the health care professional's (HCP) perception of the care of older adults and how ageist attitudes or perspectives may impact
Aaron P. Smith, Pooja M. Achanta, Jiha Lee, Namrata Singh, Una E. Makris   +4 more
wiley   +1 more source

Optimal control of susceptible mature pest concerning disease-induced pest-natural enemy system with cost-effectiveness

Computational and Mathematical Biophysics
This article addresses the pressing issue of pest outbreaks in India, which poses significant challenges for farmers and ecologists. A novel system is proposed for effective control that leverages natural enemies.
Mathur Kunwer Singh, Kumar Bhagwan
doaj   +1 more source

Cytocrystalloscopy and its Methodical Variants [PDF]

Journal of Stress Physiology & Biochemistry, 2019
The purpose of the work is consideration of the assumptions and the rationale for the new diagnostic laboratory technology – cytocrystalloscopy, as well as variants of its implementation.
Andrew K. Martusevich, Maria A. Feofilova, Lida K. Kovaleva, Elena S. Golygina   +3 more
doaj