Results 111 to 120 of about 1,623,979 (311)

The impact of frailty syndrome on skeletal muscle histology: preventive effects of exercise

open access: yesFEBS Open Bio, EarlyView.
Frailty syndrome exacerbates skeletal muscle degeneration via increased ECM deposition and myofiber loss. This study, using a murine model, demonstrates that endurance exercise attenuates these histopathological alterations, preserving muscle integrity. Findings support exercise as a viable strategy to counteract frailty‐induced musculoskeletal decline
Fujue Ji   +3 more
wiley   +1 more source

Development of Aβ and anti-Aβ dynamics models for Alzheimer’s disease

open access: yesComputational and Mathematical Biophysics
Alzheimer’s disease is one of the most prevalent types of dementia worldwide. It is caused by the accumulation of amyloid-beta (Aβ) plaques in the brain, disrupting communication pathways and memory.
Cindyawati Cindyawati   +3 more
doaj   +1 more source

The role of circular RNAs in regulating cytokine signaling in cancer

open access: yesFEBS Open Bio, EarlyView.
Cytokines present in the tumor microenvironment fuel cancer development. Aberrant expression of circRNAs contributes to cancer progression. Cytokines are involved in regulating circRNA biogenesis. Furthermore, aberrantly expressed circRNAs regulate the expression of ligands, receptors, and downstream effectors involved in cytokine signaling to promote ...
Vandana Joshi   +4 more
wiley   +1 more source

Augmenting heart disease prediction with explainable AI: A study of classification models

open access: yesComputational and Mathematical Biophysics
Although heart disease stands as a prominent contributor to worldwide deaths, not all individuals affected by it ultimately fall prey to its effects. Timely diagnosis and effective treatment can offer those with heart conditions a high-quality life in ...
Titti Raja Rani   +2 more
doaj   +1 more source

Spatial Data Analysis with GIS: An Introduction to Application in the Social Sciences (92-10)

open access: yes, 1992
An attention to location, spatial interaction, spatial structure and spatial processes lies at the heart of research in several subdisciplines in the social sciences. Empirical studies in these fields routinely employ data for which locational attributes (the "where") are an important source of information.
openaire   +1 more source

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

open access: yesFEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian   +6 more
wiley   +1 more source

Matrix: a complex amalgam of structures and functions in tumor microenvironment

open access: yesFEBS Open Bio, EarlyView.
The matrix is a dynamic, intricate three‐dimensional mesh of biomolecules with both structural and functional properties. This review deals with the complexity of this ‘molecular amalgam’ in the tumor microenvironment and highlights its importance in the maintenance and evolution of tumors by describing certain matrix biomolecules, such as ...
Spyros S. Skandalis   +3 more
wiley   +1 more source

Optimal control of susceptible mature pest concerning disease-induced pest-natural enemy system with cost-effectiveness

open access: yesComputational and Mathematical Biophysics
This article addresses the pressing issue of pest outbreaks in India, which poses significant challenges for farmers and ecologists. A novel system is proposed for effective control that leverages natural enemies.
Mathur Kunwer Singh, Kumar Bhagwan
doaj   +1 more source

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