Results 111 to 120 of about 11,820,454 (341)
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Metaphor Processing in Schizophrenia Patients: A Study of Comprehension and Explanation of Metaphors
Psychology of Language and Communication, 2017 The study assessed the quantity and quality of errors made by schizophrenia patients in understanding and interpretation of the same metaphors, to evaluate metaphor understanding and explanation depending on the type of presentation material, and to ...
Pawełczyk Agnieszka +2 more
doaj +1 more source
, 1996 Introduction -- Explanation of Plant Evaluation Tables -- Table 1. Weather records for the test years -- Table 2. All plant materials evaluated in 1996 -- Table 3. All plants that have been evaluated but did not survive the minimum number of test years --
Holloway, Patricia S. +4 more
core +1 more source
Flavor Asymmetry of the Nucleon Sea: Consequences for Dilepton Production
, 1992 Parton distributions derived from a chiral quark model that generates an excess of down quarks and antiquarks in the proton's sea satisfactorily describe the measured yields of muon pairs produced in proton-nucleus collisions.
A. D. Martin +15 more
core +2 more sources
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
On building machine learning models for medical dataset with correlated features
Computational and Mathematical BiophysicsThis work builds machine learning models for the dataset generated using a numerical model developed on an idealized human artery. The model has been constructed accounting for varying blood characteristics as it flows through arteries with variable ...
Nayak Debismita +1 more
doaj +1 more source
European Journal of Applied MathematicsNumerous evolution equations with nonlocal convolution-type interactions have been proposed. In some cases, a convolution was imposed as the velocity in the advection term.
Hideki Murakawa, Yoshitaro Tanaka
doaj +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source