Results 21 to 30 of about 938 (156)
An in-host model of HIV incorporating latent infection and viral mutation [PDF]
, 2015 We construct a seven-component model of the in-host dynamics of the Human Immunodeficiency Virus Type-1 (i.e, HIV) that accounts for latent infection and the propensity of viral mutation. A dynamical analysis is conducted and a theorem is presented which
A. Perelson +10 more
core +1 more source
Bifurcation-based parameter tuning in a model of the GnRH pulse and surge generator [PDF]
, 2008 We investigate a model of the GnRH pulse and surge generator, with the definite aim of constraining the model GnRH output with respect to a physiologically relevant list of specifications. The alternating pulse and surge pattern of secretion results from
Alexandre Vidal +3 more
core +5 more sources
Nonautonomous Dynamical Systems, 2023 In this article, we consider an epidemiological model in which we take into account the effects of direct and indirect transmissions. The first mode occurs through direct contact between infectious and susceptible individuals, and the second one will ...
Najm Fatiha +4 more
doaj +1 more source
Computational and Mathematical Methods in Medicine, Volume 11, Issue 3, Page 201-222, 2010., 2010 A deterministic compartmental sex‐structured HIV/AIDS model for assessing the effects of homosexuals and bisexuals in heterosexual settings in which homosexuality and bisexuality issues have remained taboo is presented. We extend the model to focus on the effects of condom use as a single strategy approach in HIV prevention in the absence of any other ...
Noble Malunguza +3 more
wiley +1 more source
Dynamics of an eco-epidemic model with Allee effect in prey and disease in predator
Computational and Mathematical Biophysics, 2023 In this work, the dynamics of a food chain model with disease in the predator and the Allee effect in the prey have been investigated. The model also incorporates a Holling type-III functional response, accounting for both disease transmission and ...
Kumar Bipin, Sinha Rajesh Kumar
doaj +1 more source
Optimal Control of Vertically Transmitted Disease: An Integrated Approach
Computational and Mathematical Methods in Medicine, Volume 11, Issue 4, Page 369-387, 2010., 2010 We study the dynamics of a disease under administration of a vaccine and antiviral drug, where the disease transmits directly from the parents to the offspring (vertical transmission) and also through contact with infective individuals (horizontal transmission).
Samit Bhattacharyya, Suma Ghosh
wiley +1 more source
Homoclinic and heteroclinic solutions to a hepatitis C evolution model
Open Mathematics, 2018 Homoclinic and heteroclinic solutions to a standard hepatitis C virus (HCV) evolution model described by T. C. Reluga, H. Dahari and A. S. Perelson, (SIAM J. Appl. Math., 69 (2009), pp. 999–1023) are considered in this paper.
Telksnys Tadas +4 more
doaj +1 more source
Geometric medians in reconciliation spaces [PDF]
, 2017 In evolutionary biology, it is common to study how various entities evolve together, for example, how parasites coevolve with their host, or genes with their species.
Huber, Katharina T. +3 more
core +4 more sources
Mathematical Modelling of Immune Response in Tissues
Computational and Mathematical Methods in Medicine, Volume 10, Issue 1, Page 9-38, 2009., 2009 We have developed a spatial–temporal mathematical model (PDE) to capture fundamental aspects of the immune response to antigen. We have considered terms that broadly describe intercellular communication, cell movement, and effector function (activation or inhibition).
B. Su +3 more
wiley +1 more source
A Mathematical Model Quantifies Proliferation and Motility Effects of TGF‐β on Cancer Cells
Computational and Mathematical Methods in Medicine, Volume 10, Issue 1, Page 71-83, 2009., 2009 Transforming growth factor (TGF)‐β is known to have properties of both a tumour suppressor and a tumour promoter. While it inhibits cell proliferation, it also increases cell motility and decreases cell–cell adhesion. Coupling mathematical modelling and experiments, we investigate the growth and motility of oncogene‐expressing human mammary epithelial ...
Shizhen Emily Wang +6 more
wiley +1 more source