Results 61 to 70 of about 1,208,315 (263)
Spatiotemporal clustering of cutaneous leishmaniasis in Fars province, Iran
Asian Pacific Journal of Tropical Biomedicine, 2017 Objective: To assess the spatiotemporal trait of cutaneous leishmaniasis (CL) in Fars province, Iran. Methods: Spatiotemporal cluster analysis was conducted retrospectively to find spatiotemporal clusters of CL cases.
Marjan Zare +5 more
doaj +1 more source
Gastric Ewing Sarcoma identified on a Meckel's scan
Radiology Case Reports, 2020 Ewing Sarcoma is a malignant small round blue cell tumor most commonly found in bones and soft tissues of the axial skeleton and extremities. The Ewing family of tumors, including peripheral neuroectodermal tumor, represent the second most common ...
Lavi Nissim, MD, Gerald Mandell, MD
doaj +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Scan speed affects quantitative optical coherence tomography angiography vascular metrics
Scientific ReportsOptical coherence tomography angiography (OCTA) offers the possibility of obtaining objective quantification of retinal vasculature, with increasing utility as biomarkers for both systemic and ocular diseases.
Lourdes Vidal-Oliver +4 more
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Crisis and Change: A University Press Environmental Scan
Journal of Librarianship and Scholarly Communication, 2014 A transcript of the closing keynote address delivered March 6, 2014 at the inaugural Library Publishing Forum in Kansas City, Missouri.
Peter Berkery
doaj +2 more sources
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Heavy Vehicle Road Safety: A Scan of Recent Literature
Journal of Road Safety, 2011 The number of registered heavy vehicles (HV) in Australia has risen by 22% since 2005 and, with the national freight task projected to double by 2030, the number of HVs on Australian roads will continue to increase.
S Raftery, J Grigo, J Woolley
doaj