Results 121 to 130 of about 84,425,241 (312)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

No complexity-stability relationship in natural ecosystems [PDF]

open access: yes, 2012
Understanding the mechanisms responsible for the stability and persistence of natural ecosystems is one of the greatest challenges in ecology. Robert May showed that contrary to intuition, complex randomly built communities are less likely to be stable ...
Jacquet, Claire - Jean-Pierre
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

GOALDS – Goal Based Damaged Stability: Collision and Grounding Damages [PDF]

open access: yes, 2011
The present paper outlines the current status of work of the EU funded, FP7 project GOALDS (Goal Based Damaged Stability, 2009-2012), which aims at addressing shortcomings of SOLAS 2009 with respect to the survivability assessment of passenger ships by ...
Papanikolaou A.   +2 more
core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Structural stability research council: proceedings 1980 [PDF]

open access: yes, 1980
One of the purposes of the Council is to maintain a forum where structural stability aspects of the behavior of frames, columns and other compression-type elements in metal and compression structures can be presented for evaluation and discussion.
Structural stability research council
core   +1 more source

Measures and Stability in a Model, revisited

open access: yesҚарағанды университетінің хабаршысы. Математика сериясы
This article is written in honor of the 8th Kazakh–French Logical Colloquium. We expand on an unpublished research note of the second author. We record some results concerning local Keisler measures with respect to a formula which is stable in a model ...
C.M.B.J. D’Elb´ee, K.A.C. Gannon
doaj   +1 more source

Home - About - Disclaimer - Privacy