Results 21 to 30 of about 114,629,970 (270)

Les représentations en psychologie du travail, de la formation, et en didactique des disciplines scientifiques

Recherches en Éducation, 2013
The paper proposes a tour d’horizon of the notion of « representation » and the use of the term, in the general framework of cognitive psychology; its polysemy and multidimensional caracteristics are recalled.
Janine Rogalski
doaj   +1 more source

«Żadnej metafizyki. Idioci!»: Teatr postdramatyczny – ateizm – polityka

Pamiętnik Teatralny, 2017
This article undertakes a reading of Tadeusz Różewicz’s open theatre, particularly The Interrupted Act and The Card Index, in accordance with the sequence defined in the subtitle: postdramatic theatre, atheism, and politics.
Marcin Kościelniak
doaj   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

Advanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong, Ming Ho Yam, Jiaxin Zhang, Lin Du, Linbin Zhou, Yolanda Wong Ying Yip, Bo Man Ho, Hemlata Bisnauthsing, Jiahui Li, Ivan Kong, Shushu Xu, Changzhen Fu, Karl K.H. So, Joaquim S.L. Vong, Ling‐Ping Cen, Ming‐Ming Yang, Khazeema Yousaf, Mai Har Sham, Sun On Chan, Poemen P. Chan, Chi Pui Pang, Clement C. Tham, Jing Na He, Jian Li, Wai Kit Chu   +24 more
wiley   +1 more source

Synergistic Spin‐Polarization and Single‐Atom Engineering in Magnetic Heterojunctions for Efficient Solar Water Splitting

Advanced Science, EarlyView.
High‐throughput screening led to the identification of 67 Z‐scheme heterojunctions (comprising 2D magnetic transition metal halides and non‐magnetic transition metal chalcogenides). For CrI3/MoTe2 and CrI3/WTe2, electronic structure analysis demonstrated that synergistic crystallographic point group and built‐in electric field effects generate a ...
Hongyang Ren, Zhenzhou Guo, Huirong Wu, Peilin Huang, Jie Yang, Jie Zhang, Guangqian Ding, Hongkuan Yuan, Biao Wang   +8 more
wiley   +1 more source

Early Retinal UCHL1 Dysregulation Coupled With Synaptic Loss Reflects Alzheimer's Disease Severity

Advanced Science, EarlyView.
This study identifies synapse‐enriched deubiquitinase UCHL1 as an early Aβ‐responsive regulator of retinal synaptopathy in Alzheimer's disease. Retinal UCHL1 loss accompanies excitatory synapse degeneration, p75NTR activation, and neuroinflammation, and predicts Braak stage and cognitive decline. Aβ42 fibrils trigger synaptic and UCHL1 depletion before
Altan Rentsendorj, Jean‐Philippe Vit, Alexandre Hutton, Yosef Koronyo, Saba Shahin, Edward Robinson, Ernesto Barron, Anthony Rodriguez, Ousman Jallow, Julia Sheyn, Bhakta Prasad Gaire, Lalita Subedi, Miyah R. Davis, Barathan Gnanabharathi, Alexander V. Ljubimov, Stuart L. Graham, Vivek K. Gupta, Mehdi Mirzaei, Debra Hawes, Katlin Silm, Keith L. Black, Lon S. Schneider, Alfredo A. Sadun, Jesse G. Meyer, Dieu‐Trang Fuchs, Maya Koronyo‐Hamaoui   +25 more
wiley   +1 more source

Stakeholder reactions to new policies for forest-biodiversity protection Stakeholder reactions to new policies for forest-biodiversity protection [PDF]

Sciences, Eaux & Territoires, 2011
The capacity to determine in advance the behaviour of stakeholders in charge of implementing public policies and to foresee the reactions of the public and consumers impacted by those policies would be a decisive advantage for decision-makers.
Jean-Paul Bousset, Claire Choquet, Catherine Macombe and Monique Bouchaud
doaj  

6.1% Volumetric Negative Thermal Expansion Induced by the Reversible Reconstructive Phase Transition in Pb‐Free Bi1−xLnxCoO3 (Ln: Lanthanoid)

Advanced Science, EarlyView.
Perovskite‐type oxide lanthanoid‐substituted BiCoO3 exhibits a reversible negative thermal expansion (NTE) originated from the coordination change from the CoO5 pyramid to the CoO6 octahedron due to melting of the dxy orbital ordering in the d6 electron configuration, and the 6.1% volume shrinkage in Bi0.82Nd0.18CoO3 is the largest ever observed in the
Yuki Sakai, Kazuki Takahashi, Shogo Wakazaki, Takumi Nishikubo, Jun Miyake, Takehiro Koike, Teppei Nagase, Takafumi Yamamoto, Kano Hatayama, Masaichiro Mizumaki, Masaki Azuma   +10 more
wiley   +1 more source

Encapsulation of the HSP-90 Chaperone Inhibitor 17-AAG in Stable Liposome Allow Increasing the Therapeutic Index as Assessed, in vitro, on Leishmania (L) amazonensis Amastigotes-Hosted in Mouse CBA Macrophages

Frontiers in Cellular and Infection Microbiology, 2018
The current long-term treatment for leishmaniasis causes severe side effects and resistance in some cases. An evaluation of the anti-leishmanial potential of an HSP90-inhibitor, 17-allylamino-17-demethoxygeldanamycin (17-AAG), demonstrated its potent ...
Antonio Luis de Oliveira Almeida Petersen, Thiers A. Campos, Thiers A. Campos, Diana Angélica dos Santos Dantas, Juliana de Souza Rebouças, Juliana de Souza Rebouças, Juliana Cruz da Silva, Juliana P. B. de Menezes, Fábio R. Formiga, Fábio R. Formiga, Janaina V. de Melo, Giovanna Machado, Patrícia S. T. Veras, Patrícia S. T. Veras   +13 more
doaj   +1 more source

Basal Plane Graphene Coated Zn Powder for High Performance Aqueous Zn Metal Batteries

Advanced Science, EarlyView.
A mechanofusion‐driven dry coating forms a hydrophobic graphene shell on Zn powder, stabilizing the electrode‐electrolyte interface. This basal‐plane‐rich protective layer modifies the Zn2+ solvation environment and promotes preferential growth along the (002) plane, suppressing dendrite and parasitic reactions.
Dongju Kim, Daebeom Jeong, Kijung Kim, Van‐Chuong Ho, Jongsoon Kim, Hun‐Gi Jung, Jung Ho Kim, Goojin Jeong, Junyoung Mun   +8 more
wiley   +1 more source