Results 91 to 100 of about 3,685,182 (335)
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Merger as Intermittent Accretion
, 2008 The Self-Similar Secondary Infall Model (SSIM) is modified to simulate a merger event. The model encompass spherical versions of tidal stripping and dynamical friction that agrees with the Syer & White merger paradigm's behaviour.
Ascasibar +27 more
core +2 more sources
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Area products for stationary black hole horizons
, 2013 Area products for multi-horizon stationary black holes often have intriguing properties, and are often (though not always) independent of the mass of the black hole itself (depending only on various charges, angular momenta, and moduli).
F. Larsen +4 more
core +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Periastron Passage Triggering of the 19th Century Eruptions of Eta Carinae
, 2010 We reconstruct the evolution of Eta Carinae in the last two centuries, under the assumption that the two 19th century eruptions were triggered by periastron passages, and by that constrain the binary parameters.
Kashi, Amit, Soker, Noam
core +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Discover Public HealthBackground Religious mass gathering events are repeated occurrences characterized by a large convergence of populations in a specific location. These events challenge local administration and infrastructure and pose several communicable and non ...
Alexandra Haută +7 more
doaj +1 more source
, 2008 A new technique for improving the precision of measurements of SUSY particle masses at the LHC is introduced. The technique involves kinematic fitting of events with two fully identified decay chains.
A. Barr +13 more
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source